Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Mendell Rimer"'
Autor:
Daniela A. Ayala, Anthony Matarazzo, Bonnie L. Seaberg, Misha Patel, Eliana Tijerina, Camryn Matthews, Gabriel Bizi, Ashton Brown, Alan Ta, Mendell Rimer, Rahul Srinivasan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Astrocytes display context-specific diversity in their functions and respond to noxious stimuli between brain regions. Astrocytic mitochondria have emerged as key players in governing astrocytic functional heterogeneity, given their ability
Externí odkaz:
https://doaj.org/article/9ac9ed9c69f24684b74fabd580afc44f
Autor:
Young il Lee, Mendell Rimer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Externí odkaz:
https://doaj.org/article/33bd6e04c0c448848b1a9d7465ea11a6
Publikováno v:
Neurosci Lett
Recent RNA-seq studies have generated a new crop of putative gene markers for terminal Schwann cells (tSCs), non-myelinating glia that cap axon terminals at the vertebrate neuromuscular junction (NMJ). While compelling, these studies did not validate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d123bc60725dc096026b3217fc0f35a
https://europepmc.org/articles/PMC8821205/
https://europepmc.org/articles/PMC8821205/
Autor:
Ximena Paez-Colasante, Bonnie Seaberg, Tara L Martinez, Lingling Kong, Charlotte J Sumner, Mendell Rimer
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75866 (2013)
In the inherited childhood neuromuscular disease spinal muscular atrophy (SMA), lower motor neuron death and severe muscle weakness result from the reduction of the ubiquitously expressed protein survival of motor neuron (SMN). Although SMA mice reca
Externí odkaz:
https://doaj.org/article/11da67e5c8b244fab0da734696be643d
Autor:
Steven Lam, Young il Lee, Zhihua Feng, Bonnie Seaberg, Chien-Ping Ko, Wesley J. Thompson, Friedrich Metzger, Pei-Fen Yen, Sergey Paushkin, Robert Louis Hastings, Mendell Rimer
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Spinal muscular atrophy (SMA) is caused by loss-of-function mutations in the survival of motoneuron gene 1 (SMN1). SMA is characterized by motoneuron death, skeletal muscle denervation and atrophy. Disease severity inversely correlates with copy numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34795520324d41f35687d39672bd4853
https://doi.org/10.1038/s41598-019-44222-2
https://doi.org/10.1038/s41598-019-44222-2
Autor:
Gary E. Landreth, Gabrielle Henslee, Mendell Rimer, Shuo Wang, Ximena Paez-Colasante, Bonnie Seaberg
Publikováno v:
Molecular and Cellular Biology. 35:1238-1253
The Ras–extracellular signal-regulated kinase 1 and 2 (ERK1/2) pathway appears to be important for the development, maintenance, aging, and pathology of mammalian skeletal muscle. Yet no gene targeting of Erk1/2 in muscle fibers in vivo has been re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cb8812ac06ddf2f91729613546e2b8
https://doi.org/10.1128/mcb.01071-14
https://doi.org/10.1128/mcb.01071-14
Publikováno v:
Scientific Reports
To test the role of extracellular-signal regulated kinases 1 and 2 (ERK1/2) in slow-twitch, type 1 skeletal muscle fibers, we studied the soleus muscle in mice genetically deficient for myofiber ERK1/2. Young adult mutant soleus was drastically waste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b101e7cc8b29642c1846030f2a0a82
http://europepmc.org/articles/PMC5373078
http://europepmc.org/articles/PMC5373078
Publikováno v:
Scientific Reports
To test the role of extracellular-signal regulated kinases 1 and 2 (ERK1/2) in slow-twitch, type 1 skeletal muscle fibers, we studied the soleus muscle in mice genetically deficient for myofiber ERK1/2. Young adult mutant soleus was drastically waste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8a8e60e9601dce3852a68306798df4
https://doi.org/10.1038/srep38745
https://doi.org/10.1038/srep38745
Publikováno v:
Developmental Biology. 356:432-444
A mouse model of the devastating human disease “spinal muscular atrophy” (SMA) was used to investigate the severe muscle weakness and spasticity that precede the death of these animals near the end of the 2nd postnatal week. Counts of motor units
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6ca49f7994e0179b5dd0fba8ed7523
https://doi.org/10.1016/j.ydbio.2011.05.667
https://doi.org/10.1016/j.ydbio.2011.05.667
Autor:
Mendell Rimer
Publikováno v:
Communicative & Integrative Biology. 4:143-146
Information between neurons and the target cells they innervate passes through sites of functional contact called synapses. How synapses form and are altered by sensory or cognitive experience is central to understand nervous system function. Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e148e4f1436a729789812f12418c71d
https://doi.org/10.4161/cib.4.2.14357
https://doi.org/10.4161/cib.4.2.14357