Zobrazeno 1 - 10
of 934
pro vyhledávání: '"Mendelian randomization study"'
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 17, Pp 2077-2088 (2024)
Pan Luo, Dejin Gao, Chenglong Wang, Rui Guo, Qingguo Zhang Department of Auricular Reconstruction, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaCorrespondence: Qi
Externí odkaz:
https://doaj.org/article/b19e11c6a31e4f9c8c871832349c92cc
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Interleukin-6 (IL-6) plays a crucial role in the pathogenesis of cardiovascular disease (CVD), and IL-6 receptor (IL-6R) blockade has emerged as a promising therapeutic option. However, their specific therapeutic effects in different types o
Externí odkaz:
https://doaj.org/article/b5cb279341bb4d8a8643f8e6a61cbbb9
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Purpose Recent observational studies have highlighted the role of altered gut microbiota (GM) in the activation of the host immune system and the resulting of gastric cancer (GC). However, the exact causal relationship and mechanisms of acti
Externí odkaz:
https://doaj.org/article/a73d93db59754e2bb63199260cc84549
Publikováno v:
BMC Urology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Urolithiasis is a highly prevalent global disease closely associated with metabolic factors; however, the causal relationship between blood metabolites and urolithiasis remains poorly understood. Method In our study, we employed a
Externí odkaz:
https://doaj.org/article/9367e472f34c4177a688a52d360a55e1
Publikováno v:
Clinical, Cosmetic and Investigational Dermatology, Vol Volume 17, Pp 1865-1874 (2024)
Gongjie Zhang,1 Xinlyu Huang,1 Hanlin Li,1 Huizi Gong,1 Yabin Zhou,2 Fang Liu1 1Department of Dermatology, Venereology and Cosmetology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, People’s Republic of China; 2Department
Externí odkaz:
https://doaj.org/article/5752cb7eebeb408c90e3102c57df186a
Autor:
Guan-yi Chen, Chao Liu, Yu Xia, Ping-xiao Wang, Zi-yue Zhao, Ao-yu Li, Chu-qiao Zhou, Cheng Xiang, Jia-lin Zhang, Yi Zeng, Peng Gu, Hui Li
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Introduction Walking stands as the most prevalent physical activity in the daily lives of individuals and is closely associated with physical functioning and the aging process. Nonetheless, the precise cause-and-effect connection between wal
Externí odkaz:
https://doaj.org/article/a29fc1a9a5ca4e849607a24a0e9b900e
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background The incidence of diabetic gastrointestinal diseases is increasing year by year. This study aimed to investigate the causal relationship between antidiabetic medications and gastrointestinal disorders, with the goal of reducing the
Externí odkaz:
https://doaj.org/article/0969f1b4e1fa4df5bf6e093d83100c26
Autor:
Jiasheng Cai, Xiaochen Sun, Mingxuan Li, Rong Luo, Wei Wang, Zilong Wang, Mohammed Ahmed Akkaif, Haibo Liu
Publikováno v:
Journal of Health, Population and Nutrition, Vol 43, Iss 1, Pp 1-10 (2024)
Abstract Background Observational studies have elucidated the associations between dietary factors and hypertension. Nevertheless, the exploration of these relationships using Mendelian randomization remains scarce currently. Methods The Mendelian ra
Externí odkaz:
https://doaj.org/article/594dd0d47f5f4224b84ef1a7258cf368
Autor:
Jiawu Yan, Zhongyuan Wang, Guojian Bao, Cailin Xue, Wenxuan Zheng, Rao Fu, Minglu Zhang, Jialu Ding, Fei Yang, Beicheng Sun
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Background Observational studies have reported that gut microbiota composition is associated with metabolic syndrome. However, the causal effect of gut microbiota on metabolic syndrome has yet to be confirmed. Methods We performed a bidirect
Externí odkaz:
https://doaj.org/article/8b130f4414d74181bcf6a3cbacafab92
Autor:
Guang-zhi Liao, Chun-hui He, Xin-qing Li, Yang Xiong, Li-yan Huang, An-ran Xin, Guo Ai, Man-qing Luo, Yu-hui Zhang, Jian Zhang
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106636- (2024)
Introduction: The bidirectional relationship between the brain cortex and cardiovascular diseases (CVDs) remains inadequately explored. Methods: This study used bidirectional Mendelian randomization (MR) analysis to explore the interactions between n
Externí odkaz:
https://doaj.org/article/05b1a95c60f046aa9710fea4907d6f2b