Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Menci Kunstelj"'
Autor:
Menci Kunstelj, Simona Jevsevar
Publikováno v:
Therapeutic Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8cea2e9e05e1135594e23ca6a78ee2
https://doi.org/10.1002/9783527644827.ch3
https://doi.org/10.1002/9783527644827.ch3
Publikováno v:
Biotechnology Journal. 5:113-128
Since the first PEGylated product was approved by the Food and Drug Administration in 1990, PEGylation has been widely used as a post-production modification methodology for improving biomedical efficacy and physicochemical properties of therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3454054e02535bb35a59d011198c2c
https://doi.org/10.1002/biot.200900218
https://doi.org/10.1002/biot.200900218
Autor:
Menci Kunstelj, Simon Caserman, Simona Jevsevar, Tanja Milunović, Mateja Kusterle, Vladka Gaberc Porekar, Mark Schiefermeier
Publikováno v:
Analytical Biochemistry. 389:27-31
Pegylation is the most widely used and accepted methodology for half-life extension of biopharmaceutical drugs that also improves physicochemical and biological characteristics of proteins considerably. Most of the positive pharmacological effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d874491cdd6470c0d78d217e404f5b
https://doi.org/10.1016/j.ab.2009.03.023
https://doi.org/10.1016/j.ab.2009.03.023