Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Menashe Bar Eli"'
Autor:
Ricardo A. de Azevedo, Einav Shoshan, Shanzhi Whang, Gal Markel, Ashvin R. Jaiswal, Arthur Liu, Michael A. Curran, Luiz R. Travassos, Menashe Bar-Eli
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Immune checkpoint blockade (ICB) has demonstrated an impressive outcome in patients with metastatic melanoma, yet, durable complete response; even with Ipilimumab/Nivolumab combo are under 30%. Primary and acquired resistance in response to ICB is co
Externí odkaz:
https://doaj.org/article/817dabb084cf48d8bce2b6b5df563d28
Autor:
Yael Nemlich, Erez Nissim Baruch, Michal Judith Besser, Einav Shoshan, Menashe Bar-Eli, Liat Anafi, Iris Barshack, Jacob Schachter, Rona Ortenberg, Gal Markel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
In metastatic melanoma, ADAR1 is downregulated, facilitating proliferation. Here, the authors show an ADAR1-dependent and RNA-editing-independent regulation of melanoma invasion mediated by ITGB3 expression, which can be reversed when ITGB3 is blocke
Externí odkaz:
https://doaj.org/article/b3931c919fb84915ae92ef05fa08880c
Autor:
Guermarie Velazquez-Torres, Einav Shoshan, Cristina Ivan, Li Huang, Enrique Fuentes-Mattei, Harrison Paret, Sun Jin Kim, Cristian Rodriguez-Aguayo, Victoria Xie, Denise Brooks, Steven J. M. Jones, A. Gordon Robertson, George Calin, Gabriel Lopez-Berenstein, Anil Sood, Menashe Bar-Eli
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
In melanoma, reduced ADAR1 impairs A-to-I microRNA editing. Here, the authors show that miR-378a-3p undergoes this editing in non-metastatic cells and the edited form of miR-378a-3p binds to the PARVA oncogene, inhibiting its expression and preventin
Externí odkaz:
https://doaj.org/article/dd20c2509c0c46dbbe02e75f436eee1a
Autor:
Isidore Rigoutsos, Sang Kil Lee, Su Youn Nam, Simone Anfossi, Barbara Pasculli, Martin Pichler, Yi Jing, Cristian Rodriguez-Aguayo, Aristeidis G. Telonis, Simona Rossi, Cristina Ivan, Tina Catela Ivkovic, Linda Fabris, Peter M. Clark, Hui Ling, Masayoshi Shimizu, Roxana S. Redis, Maitri Y. Shah, Xinna Zhang, Yoshinaga Okugawa, Eun Jung Jung, Aristotelis Tsirigos, Li Huang, Jana Ferdin, Roberta Gafà, Riccardo Spizzo, Milena S. Nicoloso, Anurag N. Paranjape, Maryam Shariati, Aida Tiron, Jen Jen Yeh, Raul Teruel-Montoya, Lianchun Xiao, Sonia A. Melo, David Menter, Zhi-Qin Jiang, Elsa R. Flores, Massimo Negrini, Ajay Goel, Menashe Bar-Eli, Sendurai A. Mani, Chang Gong Liu, Gabriel Lopez-Berestein, Ioana Berindan-Neagoe, Manel Esteller, Scott Kopetz, Giovanni Lanza, George A. Calin
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-21 (2017)
Abstract Background Non-coding RNAs have been drawing increasing attention in recent years as functional data suggest that they play important roles in key cellular processes. N-BLR is a primate-specific long non-coding RNA that modulates the epithel
Externí odkaz:
https://doaj.org/article/1e8d188da0bf4c3faa5d2b002a7f8760
Autor:
Rajesha Rupaimoole, Sherry Y. Wu, Sunila Pradeep, Cristina Ivan, Chad V. Pecot, Kshipra M. Gharpure, Archana S. Nagaraja, Guillermo N. Armaiz-Pena, Michael McGuire, Behrouz Zand, Heather J. Dalton, Justyna Filant, Justin Bottsford Miller, Chunhua Lu, Nouara C. Sadaoui, Lingegowda S. Mangala, Morgan Taylor, Twan van den Beucken, Elizabeth Koch, Cristian Rodriguez-Aguayo, Li Huang, Menashe Bar-Eli, Bradly G. Wouters, Milan Radovich, Mircea Ivan, George A. Calin, Wei Zhang, Gabriel Lopez-Berestein, Anil K. Sood
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/1ad9300d3cf4440c80b3af03df9e79a0
Autor:
Anil K. Sood, Keith A. Baggerly, Jing Wang, Menashe Bar-Eli, Eric Jonasch, Sherry Y. Wu, Einav Shoshan, Cristina Ivan, Wencai Ma, Emine Bayraktar, Lingegowda S. Mangala, Yunfei Wen, Hui Yao, Santosh K. Dasari, Michael H. McGuire
Investigations into the function of nonpromoter DNA methylation have yielded new insights into epigenetic regulation of gene expression. Previous studies have highlighted the importance of distinguishing between DNA methylation in discrete functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f4684c8362c9bb9e84df783de7f162
https://doi.org/10.1158/1541-7786.c.6545165.v1
https://doi.org/10.1158/1541-7786.c.6545165.v1
Autor:
Anil K. Sood, Keith A. Baggerly, Jing Wang, Menashe Bar-Eli, Eric Jonasch, Sherry Y. Wu, Einav Shoshan, Cristina Ivan, Wencai Ma, Emine Bayraktar, Lingegowda S. Mangala, Yunfei Wen, Hui Yao, Santosh K. Dasari, Michael H. McGuire
Supplementary Table from Gene Body Methylation of the Lymphocyte-Specific Gene CARD11 Results in Its Overexpression and Regulates Cancer mTOR Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54afb9e21c5106c451038fac2137de92
https://doi.org/10.1158/1541-7786.22526654
https://doi.org/10.1158/1541-7786.22526654
Autor:
Sherry Y. Wu, Rajesha Rupaimoole, Fangrong Shen, Sunila Pradeep, Chad V. Pecot, Cristina Ivan, Archana S. Nagaraja, Kshipra M. Gharpure, Elizabeth Pham, Hiroto Hatakeyama, Michael H. McGuire, Monika Haemmerle, Viviana Vidal-Anaya, Courtney Olsen, Cristian Rodriguez-Aguayo, Justyna Filant, Ehsan A. Ehsanipour, Shelley M. Herbrich, Sourindra N. Maiti, Li Huang, Ji Hoon Kim, Xinna Zhang, Hee-Dong Han, Guillermo N. Armaiz-Pena, Elena G. Seviour, Sue Tucker, Min Zhang, Da Yang, Laurence J. N. Cooper, Rouba Ali-Fehmi, Menashe Bar-Eli, Ju-Seog Lee, Prahlad T. Ram, Keith A. Baggerly, Gabriel Lopez-Berestein, Mien-Chie Hung, Anil K. Sood
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The formation of blood vessels in tumours, angiogenesis, is a promising target for therapy. Here, the authors show that microRNA192 has anti-angiogenic functions and negatively regulates EGR1 and HOXB9, and that delivery of this microRNA to tumours i
Externí odkaz:
https://doaj.org/article/eb7d16e04f0748669c65e11456597cc9
Autor:
Gary E. Gallick, Christopher J. Logothetis, Sue-Hwa Lin, Mian Alauddin, Yiping Shao, Bogdan A. Czerniak, Menashe Bar Eli, Sankar N. Maity, Lynnelle Thorpe, Sanchaika Gaur, Anh G. Hoang, Ana Aparicio, Yu-Chen Lee, Jian H. Song, Eleni Efstathiou, Nila U. Parikh, Paul G. Corn, Andreas Varkaris
Supplemental Figure 1 (fig. S1). Representative whole body NaF-18 PET scan images after 44 days of (A) vehicle-treated and (B) cabozantinib-treated animals. Supplemental Figure 2 (fig. S2). Effect of cabozantinib on PDX tumor growth, animal weight, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1771a12684127acc4701f3e4133b4f8d
https://doi.org/10.1158/1078-0432.22461362
https://doi.org/10.1158/1078-0432.22461362
Autor:
Colin Dinney, Menashe Bar-Eli, David McConkey, Arlene Siefker-Radtke, Hua Wang, George Calin, Ameeta Arora, Milena Nicoloso, Wei Qi, Woonyoung Choi, Meng Zhong, Liana Adam
Purpose: The epithelial-to-mesenchymal transition (EMT) is a cell development-regulated process in which noncoding RNAs act as crucial modulators. Recent studies have implied that EMT may contribute to resistance to epidermal growth factor receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3d8c9e63d5544adae6b58e2b7d997a
https://doi.org/10.1158/1078-0432.c.6517474
https://doi.org/10.1158/1078-0432.c.6517474