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Autor:
Nikolaos K. Robakis, Maria Grazia Giovannini, Tony Wong, Menalas N Pangalos, Robert D. Blitzer, Emmanuel M. Landau
Publikováno v:
Molecular Brain Research. 76:115-120
Amyloid beta peptides (Abetas) of 39-43 amino acids constitute the major protein component of the amyloid plaques found in Alzheimer's disease brain. The generation of Abetas is regulated by the phosphoinositide (PI) pathway, which commonly couples t