Zobrazeno 1 - 10
of 635
pro vyhledávání: '"Menahem, Segal"'
Autor:
Michael Telias, Menahem Segal
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Externí odkaz:
https://doaj.org/article/03b2bf3053e44f809c0c910e6740a054
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Externí odkaz:
https://doaj.org/article/61861fefd64d43b88b472a506d41981c
Calcium Sensors STIM1 and STIM2 Regulate Different Calcium Functions in Cultured Hippocampal Neurons
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2021)
There are growing indications for the involvement of calcium stores in the plastic properties of neurons and particularly in dendritic spines of central neurons. The store-operated calcium entry (SOCE) channels are assumed to be activated by the calc
Externí odkaz:
https://doaj.org/article/c1f4d822d97646488afdef492ef1c855
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Injection of corticosterone (CORT) in the dorsal hippocampus (DH) can mimic post-traumatic stress disorder (PTSD)—related memory in mice: both maladaptive hypermnesia for a salient but irrelevant simple cue and amnesia for the traumatic context. Ho
Externí odkaz:
https://doaj.org/article/4953231816a44e969808627e1e65cfa7
Autor:
Shaul Lerner, Elmira Anderzhanova, Sima Verbitsky, Raya Eilam, Yael Kuperman, Michael Tsoory, Yuri Kuznetsov, Alexander Brandis, Tevie Mehlman, Ram Mazkereth, Robert McCarter, Menahem Segal, Sandesh C.S. Nagamani, Alon Chen, Ayelet Erez, Fabienne Dietrich Alber, Talin Babikian, Heidi Bender, Christopher Boys, David Breiger, Corinna Buerger, Peter Burgard, Mina Nguyen-Driver, Benjamin Goodlett, Elizabeth Kerr, Casey Krueger, Eva Mamak, Jacqueline H. Sanz, David Schwartz, Susan Caudle, Arianna Stefanos, Rachel Tangen, Magdalena Walter, Susan Waisbren, Greta Wilkening
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2144-2153.e7 (2019)
Summary: Patients with germline mutations in the urea-cycle enzyme argininosuccinate lyase (ASL) are at risk for developing neurobehavioral and cognitive deficits. We find that ASL is prominently expressed in the nucleus locus coeruleus (LC), the cen
Externí odkaz:
https://doaj.org/article/976ff388391d44aba3c02d09b832485b
Autor:
Tamar Sapir, Michal Segal, Gayane Grigoryan, Karin M. Hansson, Peter James, Menahem Segal, Orly Reiner
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Palmitoyl-protein thioesterase 1 (PPT1) is a depalmitoylation enzyme that is mutated in cases of neuronal ceroid lipofuscinosis (NCL). The hallmarks of the disease include progressive neurodegeneration and blindness, as well as seizures. In the curre
Externí odkaz:
https://doaj.org/article/6eeddc2e21c24a2f98153361ea4cc5a7
Autor:
Menahem Segal
Publikováno v:
Frontiers for Young Minds. 11
Over 100 years ago, Nobel Prize winner Ramon y Cajal first described structures called dendritic spines, located on the surface of brain cells. Since then, scientists have been trying to understand what dendritic spines are and how they function in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd19f0a39bc4245afaa2bd191bd09b7
https://doi.org/10.3389/frym.2023.1016978
https://doi.org/10.3389/frym.2023.1016978
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Epilepsy is a devastating disease, with cognitive and emotional consequences that are not curable. In recent years, it became apparent that cannabinoids help patients to cope with epilepsy. We have studied the effects of cannabidiol (CBD) on the abil
Externí odkaz:
https://doaj.org/article/f42c625b3b0a4d6885d396202b5ad36d
Publikováno v:
EBioMedicine, Vol 2, Iss 9, Pp 1048-1062 (2015)
Down syndrome (DS) mouse models exhibit cognitive deficits, and are used for studying the neuronal basis of DS pathology. To understand the differences in the physiology of DS model neurons, we used dissociated neuronal cultures from the hippocampi o
Externí odkaz:
https://doaj.org/article/89764baa0faf465bbccecd2804134d7f
Publikováno v:
International journal of molecular sciences. 23(20)
While neuronal mitochondria have been studied extensively in their role in health and disease, the rules that govern calcium regulation in mitochondria remain somewhat vague. In the present study using cultured rat hippocampal neurons transfected wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95bb96086f567931747607bafe3c23be
https://pubmed.ncbi.nlm.nih.gov/36293178
https://pubmed.ncbi.nlm.nih.gov/36293178