Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Menadiol"'
Autor:
Monivan Chhour, Pierre Perio, Regis Gayon, Hélène Ternet-Fontebasso, Gilles Ferry, Françoise Nepveu, Jean A. Boutin, Jan Sudor, Karine Reybier
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The balance between detoxification and toxicity is linked to enzymes of the drug metabolism Phase I (cytochrome P450 or oxidoreductases) and phase II conjugating enzymes (such as the UGTs). After the reduction of quinones, the product of the reaction
Externí odkaz:
https://doaj.org/article/26bc792e0c0542f4b230c4e3914b1c67
Publikováno v:
Free Radical Biology and Medicine. 172:482-489
The selenoprotein thioredoxin reductase 1 (TrxR1; TXNRD1) participates in multiple cellular processes and is regarded as a cellular target in anti-tumor drug discovery and development. TrxR1 has been reported to reduce menadione to menadiol and to pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1beb67fdeb18bf162ef0dae7c0a02685
https://doi.org/10.1016/j.freeradbiomed.2021.06.023
https://doi.org/10.1016/j.freeradbiomed.2021.06.023
Autor:
Jordan T. Koehn, Elana J. Cope, Dean C. Crick, Heidi D. Kreckel, Nuttaporn Samart, Andrea Basile, Heide A. Murakami, Maldonado Pablo, Cameron Van Cleave, Debbie C. Crans
Publikováno v:
Canadian Journal of Chemistry. 98:307-317
Menaquinones are lipoquinones that consist of a headgroup (naphthoquinone, menadione) and an isoprenyl sidechain. They function as electron transporters in prokaryotes such as Mycobacterium tuberculosis. For these studies, we used Langmuir monolayers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2f217c413a59dce76724325a20651ac
https://doi.org/10.1139/cjc-2020-0024
https://doi.org/10.1139/cjc-2020-0024
Autor:
Chhour, Monivan, Pério, Pierre, Gayon, Regis, Ternet-Fontebasso, Hélène, Ferry, Gilles, Nepveu, Françoise, Boutin, Jean, Sudor, Jan, Reybier, Karine
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, 2021, 12, ⟨10.3389/fphar.2021.660641⟩
Frontiers in Pharmacology, 2021, 12, ⟨10.3389/fphar.2021.660641⟩
International audience; The balance between detoxification and toxicity is linked to enzymes of the drug metabolism Phase I (cytochrome P450 or oxidoreductases) and phase II conjugating enzymes (such as the UGTs). After the reduction of quinones, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::35497743e579bdd286a5f3781bbae9d3
http://europepmc.org/articles/PMC8142080
http://europepmc.org/articles/PMC8142080
Publikováno v:
Journal of Inorganic Biochemistry. 188:38-49
The oxidation of hydroquinones is of interest both due to the generation of reactive oxygen species (ROS) and to the implications to trace metal redox state. Menadione (MNQ), a typical toxicant quinone used extensively for studying the mechanisms und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6507d9d164fb191e3c4585663dfc7c42
https://doi.org/10.1016/j.jinorgbio.2018.08.007
https://doi.org/10.1016/j.jinorgbio.2018.08.007
Publikováno v:
ACS sensors. 4(6)
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a key enzyme providing cytoprotection from quinone species. In addition, it is expressed at high levels in many human tumors, such as breast cancer. Therefore, it is considered to be a potential target in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1176a76d9d9df07bb4b477c4dafda8
https://pubmed.ncbi.nlm.nih.gov/30995391
https://pubmed.ncbi.nlm.nih.gov/30995391
Belgian Federal Science Policy Office (Belspo) (grant to BD, IAP7/44, iPROS project). co-financed by the ERDF under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007728). The trihemic bacterial cytochrome c peroxidase from Escherichia coli, Yh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc81c89bf8b70ffcebc8865f3e15bad
https://hdl.handle.net/10362/111951
https://hdl.handle.net/10362/111951
Akademický článek
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Autor:
Xing, Guowei
This thesis explores the effects of pH and chloride on Cu transformations in aqueous solutions typical of both natural waters and physiological conditions: i) The effect of pH on the interaction between Cu and H2O2 in 0.7 M NaCl solution was investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b2d70217f949e9eb47cc005cead0019
Autor:
Suzanne K. Lunsford, Gul Shahzada Khan, Abdur Rauf, Shamsa Munir, Amin Badshah, Hidayat Hussain, Zia-ur-Rehman, Afzal Shah
Publikováno v:
Electrochimica Acta. 88:858-864
The redox behavior of a menadiol derivative, 4-hydroxy-5-methoxynaphthalene-1-yl acetate (HMNA) was investigated in a wide pH range by using modern electrochemical techniques. The techniques utilized in this study were cyclic voltammetry, square wave
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c9bbdcf7cb4ab8353aa1e6cf416c21c
https://doi.org/10.1016/j.electacta.2012.10.141
https://doi.org/10.1016/j.electacta.2012.10.141