Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mena Kansagara"'
Autor:
Michael P. Maher, Sandra R. Chaplan, Jing Liu, Jason C. Rech, Brian Scott, William A. Eckert, Bryan James Branstetter, Hong Ao, Anne E. Fitzgerald, Yi Liu, Nyantsz Wu, Michele C. Rizzolio, Anindya Bhattacharya, Jamie M. Freedman, Alec D. Lebsack, Nadia Swanson, J. Guy Breitenbucher, Dong H. Li, Alan D. Wickenden, Kia Sepassi, Mena Kansagara
Publikováno v:
European Journal of Pharmacology. 663:40-50
As an integrator of multiple nociceptive and/or inflammatory stimuli, TRPV1 is an attractive therapeutic target for the treatment of various painful disorders. Several TRPV1 antagonists have been advanced into clinical trials and the initial observat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ec72a42cddf9b6c3b6d41084678c9d
https://doi.org/10.1016/j.ejphar.2011.05.001
https://doi.org/10.1016/j.ejphar.2011.05.001
Autor:
Matthew L. Peterson, Bryan James Branstetter, Lin Luo, Alec D. Lebsack, Michael P. Maher, Sandra R. Chaplan, Michele C. Rizzolio, Anindya Bhattacharya, J. Guy Breitenbucher, Nadia Nasser, Hong Ao, Wei Xiao, Michael D. Hack, Mena Kansagara, Brian Scott, Alan D. Wickenden, Raymond Rynberg
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:40-46
We have identified and synthesized a series of 2,7-diamino-thiazolo[5,4-d]pyrimidines as TRPV1 antagonists. An exploration of the structure-activity relationships at the 2-, 5-, and 7-positions of the thiazolo[5,4-d]pyrimidine led to the identificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadee51d99950e2ecde1addb8a648049
https://doi.org/10.1016/j.bmcl.2008.11.024
https://doi.org/10.1016/j.bmcl.2008.11.024
Autor:
Michael P. Maher, Sandra R. Chaplan, James Guy Breitenbucher, Qi Wang, Anindya Bhattacharya, Nadia Nasser, Michael D. Hack, Jeffrey E. Merit, Hong Ao, Natalie A. Hawryluk, Mena Kansagara, Brian Scott, Alan D. Wickenden, Chui-Se Tham
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f27af5e6528695393ea31ebc45e3381
https://doi.org/10.1096/fasebj.22.1_supplement.720.12
https://doi.org/10.1096/fasebj.22.1_supplement.720.12