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Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice

Autor: Liang, Jiurong, Zhang, Yanli, Xie, Ting, Liu, Ningshan, Chen, Huaiyong, Geng, Yan, Kurkciyan, Adrianne, Mena, Jessica Monterrosa, Stripp, Barry R, Jiang, Dianhua, Noble, Paul W

Publikováno v: Nature medicine, vol 22, iss 11

Successful recovery from lung injury requires the repair and regeneration of alveolar epithelial cells to restore the integrity of gas-exchanging regions within the lung and preserve organ function. Improper regeneration of the alveolar epithelium is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::8f774da3545b7e6e86b73790be91a550
https://escholarship.org/uc/item/83w0j7w1

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Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice.

Autor: Liang J; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Zhang Y; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Xie T; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Liu N; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Chen H; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA., Geng Y; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Kurkciyan A; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Mena JM; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Stripp BR; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Jiang D; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Noble PW; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Publikováno v: Nature medicine [Nat Med] 2016 Nov; Vol. 22 (11), pp. 1285-1293. Date of Electronic Publication: 2016 Oct 03.