Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Memetcan Alacakaptan"'
Autor:
Jürgen Braunger, Thomas Wirth, M. Huber, Hubert Pehamberger, Memetcan Alacakaptan, Guido Boehmelt, Harald J. Maier, Erick R. R. Young, Hartmut Beug, Daniel Richard Marshall, Norbert Kraut, Jeffrey B. Madwed, Eva M. Wiedemann
Publikováno v:
Genes & Cancer. 1:101-114
Increasing evidence suggests that processes termed epithelial-mesenchymal transitions (EMTs) play a key role in therapeutic resistance, tumor recurrence, and metastatic progression. NF-κB signaling has been previously identified as an important path
Autor:
Christoph A. Gebeshuber, Eva-Maria Wiedemann, Sabine Maschler, Martin Schreiber, Ivana Custic, Hartmut Beug, Memetcan Alacakaptan
Publikováno v:
EMBO Molecular Medicine
Metastasis is the major cause of carcinoma-induced death, but mechanisms involved are poorly understood. Metastasis crucially involves epithelial-to-mesenchymal transition (EMT), causing loss of epithelial polarity. Here we identify Annexin A1 (AnxA1
Autor:
Agnes, Csiszar, Betül, Kutay, Silvia, Wirth, Ulrike, Schmidt, Sabine, Macho-Maschler, Martin, Schreiber, Memetcan, Alacakaptan, Georg F, Vogel, Karin, Aumayr, Lukas A, Huber, Hartmut, Beug
Publikováno v:
Breast Cancer Research : BCR
Introduction Interleukin-like epithelial-to-mesenchymal transition inducer (ILEI) is an essential cytokine in tumor progression that is upregulated in several cancers, and its altered subcellular localization is a predictor of poor survival in human
Autor:
Memetcan Alacakaptan, Christian Schuster, Gabriele Litos, Richard Moriggl, Hartmut Beug, Andrea Hoelbl, Marc A. Kerenyi, Veronika Sexl, Boris Kovacic, Gabriele Stengl, Katrin M. Fischhuber
Publikováno v:
EMBO Molecular Medicine
The large difference in phenotypes among tumour populations may stem from the stochastic origin of tumours from distinct cells - tumour cells are assumed to retain the phenotypes of the cells from which they derive. Yet, functional studies addressing
Autor:
Rupert Oberauer, Martin Schreiber, Martin Jechlinger, Hartmut Beug, Annamaria Gal, Thomas Brabletz, Memetcan Alacakaptan, Thomas Waerner, Ido Tamir
Publikováno v:
University of Brighton
Erk/MAPK and TGFbeta signaling cause epithelial to mesenchymal transition (EMT) and metastasis in mouse mammary epithelial cells (EpH4) transformed with oncogenic Ras (EpRas). In trials to unravel underlying mechanisms, expression profiling for EMT-s