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pro vyhledávání: '"Membrane transport and intracellular motility IGMD 9: Renal disorder [NCMLS 5]"'
Autor:
Marieke Schreurs, Jeroen DeGroot, Heleen M. Wortelboer, Maarten T. Huisman, E. van de Steeg, Kitty C.M. Verhoeckx, Roeland Hanemaaijer, D. Ripken, Miriam Verwei, Rick Greupink, Frans G. M. Russel, Irene Nooijen, Maria L. H. Vlaming, Mario Monshouwer
Publikováno v:
Drug Metabolism and Disposition, 41, 3, pp. 592-601
Drug Metabolism and Disposition, 41, 592-601
Drug Metabolism and Disposition, 41, 592-601
Organic anion-transporting polypeptide 1B1 (OATP1B1) is an important hepatic uptake transporter, of which the polymorphic variant OATP1B1*15 (Asn130Asp and Val174Ala) has been associated with decreased transport activity. Rosuvastatin is an OATP1B1 s