Zobrazeno 1 - 10 of 1 322 pro vyhledávání: '"Membrane receptor signaling"'
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Akademický článek
Estrogen receptors promote NSCLC progression by modulating the membrane receptor signaling network: a systems biology perspective
Autor: Xiujuan Gao, Yue Cai, Zhuo Wang, Wenjuan He, Sisi Cao, Rong Xu, Hui Chen
Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Background Estrogen receptors (ERs) are thought to play an important role in non-small cell lung cancer (NSCLC). However, the effect of ERs in NSCLC is still controversial and needs further investigation. A new consideration is that ERs may
Externí odkaz: https://doaj.org/article/0b895de544414316850f81bfabc0f519
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2
Integration of gene co-expression analysis and multi-class SVM specifies the functional players involved in determining the fate of HTLV-1 infection toward the development of cancer (ATLL) or neurological disorder (HAM/TSP)
Autor: Mohadeseh Zarei Ghobadi, Rahman Emamzadeh
Publikováno v: PLoS ONE, Vol 17, Iss 1, p e0262739 (2022)
PLoS ONE
Human T-cell Leukemia Virus type-1 (HTLV-1) is an oncovirus that may cause two main life-threatening diseases including a cancer type named Adult T-cell Leukemia/Lymphoma (ATLL) and a neurological and immune disturbance known as HTLV-1 Associated Mye
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87adba282a2ba8e47a4158553dc4c0f5
https://doaj.org/article/a8463c6226cb44a9bfa43d9d04c09bf6
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3
Transcriptome profiling reveals new insights into the roles of neuronal nitric oxide synthase on macrophage polarization towards classically activated phenotype
Autor: Quan Sun, Hao Gao, Ping-An Chang, Feifei Huang, Xiaohong He
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257908 (2021)
In response to various stimuli, naïve macrophages usually polarize to M1 (classically activated) or M2 (alternatively activated) cells with distinct biological functions. Neuronal nitric oxide synthase (NOS1) is involved in M1 macrophage polarizatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd34e2415fbd2477974b4de8ade5977d
http://europepmc.org/articles/PMC8480887
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4
Tramtrack acts during late pupal development to direct ant caste identity
Autor: Shelley L. Berger, Karl M. Glastad, Linyang Ju
Publikováno v: PLoS Genetics, Vol 17, Iss 9, p e1009801 (2021)
PLoS Genetics
A key question in the rising field of neuroepigenetics is how behavioral plasticity is established and maintained in the developing CNS of multicellular organisms. Behavior is controlled through systemic changes in hormonal signaling, cell-specific r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0115c748e09680c58f4bc1b4ba0b1a78
https://doaj.org/article/091c4f39037a43fabe0f5ac2ad203492
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5
Parasite effectors target helper NLRs in plants to suppress immunity-related cell death
Autor: Nathan Meier, Yuan-Yuan Li, Savithramma P. Dinesh-Kumar
Publikováno v: PLoS biology, vol 19, iss 9
PLoS Biology, Vol 19, Iss 9, p e3001395 (2021)
PLoS Biology
In plants, nucleotide-binding domain and leucine-rich repeat (NLR)-containing proteins can form receptor networks to confer hypersensitive cell death and innate immunity. One class of NLRs, known as NLR required for cell death (NRCs), are central nod
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d5c08a14c39d2a71209b7e5e8e469c
https://escholarship.org/uc/item/95r65261
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6
Evidence of stereotyped contact call use in narwhal (Monodon monoceros) mother-calf communication
Autor: Susanna B. Blackwell, Outi M. Tervo, Audra E. Ames, Mads Peter Heide-Jørgensen
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0254393 (2021)
Narwhals (Monodon monoceros) are gregarious toothed whales that strictly reside in the high Arctic. They produce a broad range of signal types; however, studies of narwhal vocalizations have been mostly descriptive of the sounds available in the spec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8718438ff5dbd6ca5587eb3af47ab6ea
http://europepmc.org/articles/PMC8396719
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7
Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells
Autor: Ling Zhan, Nai-Yuan Nicholas Chang, Yvonne L. Kapila, Sean Ganther, J. Christopher Fenno, Allan Radaic, Pachiyappan Kamarajan, Erin Malone, Christian Tafolla
Publikováno v: PLoS pathogens, vol 17, iss 7
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 7, p e1009311 (2021)
Periodontal disease is driven by dysbiosis in the oral microbiome, resulting in over-representation of species that induce the release of pro-inflammatory cytokines, chemokines, and tissue-remodeling matrix metalloproteinases (MMPs) in the periodonti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31203ad6f23619c7c740a06c3d769a22
https://escholarship.org/uc/item/1dx785v1
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8
Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice
Autor: Tom Macpherson, Takatoshi Hikida, Masahiro Oka, Emiko Kasahara, Tetsuji Moriyama, Atsuo Sekiyama, Taichi Itou, Koki Sakurai, Makiko Morita, Yoichi Miyamoto, Yoshihiro Yoneda, Takaaki Ozawa
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0258364 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
Importin α1/KPNA1 is a member of the Importin α family widely present in the mammalian brain and has been characterized as a regulator of neuronal differentiation, synaptic functionality, and anxiety-like behavior. In humans, a de novo mutation of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31e6fa6d8ab4a12833e105060c34cb4
https://pubmed.ncbi.nlm.nih.gov/34767585
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9
Single-cell immunoblotting resolves estrogen receptor-α isoforms in breast cancer
Autor: Mark D. Pegram, Chi-Chih Kang, John J. Kim, Amy E. Herr, Wenchuan Liang
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0254783 (2021)
An array of isoforms of the nuclear estrogen receptor alpha (ER-α) protein contribute to heterogeneous response in breast cancer (BCa); yet, a single-cell analysis tool that distinguishes the full-length ER-α66 protein from the activation function-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa88c123647fb7fbbd1556d6a76fee7e
http://europepmc.org/articles/PMC8315538
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10
Effects of juvenile hormone in fertility and fertility-signaling in workers of the common wasp Vespula vulgaris
Autor: Andreas Bienstman, Cintia Akemi Oi, Rafael Carvalho da Silva, Tom Wenseleers, Fabio S. Nascimento, Helena Mendes Ferreira
Publikováno v: PLoS ONE, Vol 16, Iss 5, p e0250720 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE
In the highly eusocial wasp, Vespula vulgaris, queens produce honest signals to alert their subordinate workers of their fertility status, and therefore they are reproductively suppressed and help in the colony. The honesty of the queen signals is li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7443884ce7df7242e9e9d0863898db
https://lirias.kuleuven.be/handle/123456789/675619
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