Výsledky vyhledávání - "Membrane Proteins/genetics/metabolism"

Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions

Autor: Birgit Kastberger, Adrien Joly, Ralph T. Böttcher, Reinhard Fässler, Zeynep Karatas, Bernhard Wehrle-Haller, Thomas Orré, Jean-Baptiste Sibarita, Clément Cabriel, Olivier Rossier, Sandrine Lévêque-Fort, Grégory Giannone

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-23372-w⟩
Nature Communications, Vol. 12, No 1 (2021) P. 3104

Focal adhesions (FAs) initiate chemical and mechanical signals involved in cell polarity, migration, proliferation and differentiation. Super-resolution microscopy revealed that FAs are organized at the nanoscale into functional layers from the lower

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be7bdfd2d20dc2e0620ed615b9b52da
https://doaj.org/article/6de17fc1d26942499cf5255b08893432

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The macrophage-expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish

Autor: Etienne Gomez, Sowmya lyer, Valérie Wittamer, Mireia Rovira, Julien Y. Bertrand, Magali Miserocchi, David M. Langenau, Giuliano Ferrero

Publikováno v: Journal of leukocyte biology, 107 (3
Journal of Leukocyte Biology, Vol. 107, No 3 (2020) pp. 431-443
Journal of Leukocyte Biology

The mononuclear phagocytic system consists of many cells, in particular macrophages, scattered throughout the body. However, there is increasing evidence for the heterogeneity of tissue‐resident macrophages, leading to a pressing need for new tools

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88653dd66d548a18d8d623fa4620327
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/301606

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TonB-dependent receptor repertoire of Pseudomonas aeruginosa for uptake of siderophore-drug conjugates

Autor: Lena Mazza, Lucile Moynié, Alexandre Luscher, Dirk Bumann, Thilo Köhler, James H. Naismith, Pamela Saint Auguste, Daniel Pletzer

Publikováno v: 'Antimicrobial Agents and Chemotherapy ', vol: 62, pages: e00097-18-1-e00097-18-11 (2018)
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, Vol. 62, No 6 (2018) pp. e00097-18

The conjugation of siderophores to antimicrobial molecules is an attractive strategy to overcome the low outer membrane permeability of Gram-negative bacteria. In this Trojan horse approach, the transport of drug conjugates is redirected via TonB-dep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69a3a25ad4ea849316b3621b9867ed1
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:51208

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Escherichia coli SecG Is Required for Residual Export Mediated by Mutant Signal Sequences and for SecY-SecE Complex Stability

Autor: Filo Silva, Dominique Belin, Giuseppe Plaia, Yasmine Mounira Boulfekhar

Publikováno v: Journal of Bacteriology, Vol. 197, No 3 (2015) pp. 542-52

Protein export to the bacterial periplasm is achieved by SecYEG, an inner membrane heterotrimer. SecY and SecE are encoded by essential genes, while SecG is not essential for growth under standard laboratory conditions. Using a quantitative and sensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38786da1113fcaf9e56cc63c8cf90c1e
https://doi.org/10.1128/jb.02136-14

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Chromatin-Bound MDM2 regulates serine metabolism and redox homeostasis independently of p53

Autor: Thierry Levade, Jean-Charles Portais, Romain Riscal, Maud Heuillet, Madi Y. Cissé, Floriant Bellvert, Frédérique Sabourdy, Pierre Thibaut, Eric Bonneil, Emilie Schrepfer, Laurent Le Cam, Giuseppe Arena, Laetitia K. Linares, Jean-Emmanuel Sarry, Imade Ait-Arsa, Jean-Christophe Marine, Florian Rambow, Charles Vincent

Publikováno v: Molecular Cell
Molecular Cell, 2016, 62 (6), pp.890-902. ⟨10.1016/j.molcel.2016.04.033⟩
Molecular Cell, Elsevier, 2016, 62 (6), pp.890-902. ⟨10.1016/j.molcel.2016.04.033⟩

The mouse double minute 2 (MDM2) oncoprotein is recognized as a major negative regulator of the p53 tumor suppressor, but growing evidence indicates that its oncogenic activities extend beyond p53. Here, we show that MDM2 is recruited to chromatin in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4544e00da2461a9c18041ad9492c37dd
https://hal.science/hal-01886397

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TM9/Phg1 and SadA proteins control surface expression and stability of SibA adhesion molecules inDictyostelium

Autor: Pierre Cosson, Nathalie Cherix, Sophie Cornillon, Marion Le Coadic, Jackie Perrin, Romain Bruno Froquet

Publikováno v: Molecular Biology of the Cell
Molecular Biology of the Cell, Vol. 23, No 4 (2012) pp. 679-86
Molecular biology of the cell

ETOC: TM9/Phg1 proteins are essential for cellular adhesion in many systems, from Dictyostelium to human cells, yet their exact role remains unknown. We demonstrate that TM9 proteins participate in adhesion in Dictyostelium cells by controlling the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482f305f484e56892dd37f826d44bf98
https://doi.org/10.1091/mbc.e11-04-0338

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The posttranslocational chaperone lipoprotein PrsA is involved in both glycopeptide and oxacillin resistance in Staphylococcus aureus

Autor: Daniel Pablo Lew, Antoinette Monod, Diego O. Andrey, Adriana Renzoni, Ambre Jousselin, William L. Kelley

Publikováno v: Antimicrobial agents and chemotherapy
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, Vol. 56, No 7 (2012) pp. 3629-3640

Understanding in detail the factors which permit Staphylococcus aureus to counteract cell wall-active antibiotics is a prerequisite to elaborating effective strategies to prolong the usefulness of these drugs and define new targets for pharmacologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4106496f4abcd770888a928a1186c6f4

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Local Cytosolic Ca2+ Elevations Are Required for Stromal Interaction Molecule 1 (STIM1) De-oligomerization and Termination of Store-operated Ca2+ Entry

Autor: Maud Frieden, Nicolas Demaurex, Wei-Wei Shen

Publikováno v: The Journal of Biological Chemistry
The Journal of biological chemistry
Journal of Biological Chemistry, Vol. 286, No 42 (2011) pp. 36448-59

Background: STIM1 oligomerization upon endoplasmic reticulum (ER) Ca2+ depletion activates store-operated Ca2+ entry (SOCE) channels, but whether this mechanism is reversible is unknown. Results: STIM1 de-oligomerization upon ER Ca2+ refilling requir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1239165f14308202827d94c5c9e9c34d
https://doi.org/10.1074/jbc.m111.269415

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Chloroplast Biogenesis Controlled by DELLA-TOC159 Interaction in Early Plant Development

Autor: Hicham Chahtane, Venkatasalam Shanmugabalaji, Sonia Accossato, Luis Lopez-Molina, Felix Kessler, Michèle Rahire, Guillaume Gouzerh

Publikováno v: Current Biology, Vol. 28, No 16 (2018) pp. 2616-2623

Chloroplast biogenesis, visible as greening, is the key to photoautotrophic growth in plants. At the organelle level, it requires the development of non-photosynthetic, color-less proplastids to photosynthetically active, green chloroplasts at early

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb44248cb8e1f5972b86df803ce751d
https://doi.org/10.1016/j.cub.2018.06.006

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