Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs

Autor: Kay Grünewald, Cedric Leyrat, Pascale Schellenberger, Miriam Carolin Stoeber, Ari Helenius, C. Alistair Siebert

Publikováno v: Proceedings of the National Academy of Sciences, Vol. 113, No 50 (2016) pp. E8069-E8078
'Proceedings of the National Academy of Sciences of the USA ', vol: 113, pages: E8069-E8078 (2016)
Europe PubMed Central

Caveolae are invaginated plasma membrane domains involved in mechanosensing, signaling, endocytosis, and membrane homeostasis. Oligomers of membrane-embedded caveolins and peripherally attached cavins form the caveolar coat whose structure has remain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff26269255a99a86f789c6ce9c294679
https://doi.org/10.1073/pnas.1616838113

Conversion of a transmembrane to a water-soluble protein complex by a single point mutation

Autor: F. G. van der Goot, Yulia Tsitrin, Marie-Claire Velluz, Patrick Paumard, Catherine El Bez, Michael W. Parker, Salvatore Lanzavecchia, Jacques Dubochet, Marc Adrian, Craig J. Morton

Publikováno v: Nature Structural Biology. 9:729-733

Proteins exist in one of two generally incompatible states: either membrane associated or soluble. Pore-forming proteins are exceptional because they are synthesized as a water-soluble molecule but end up being located in the membrane -- that is, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87f6495c8d77e7ef1da2d32d2a2c6d9
https://doi.org/10.1038/nsb839

Rhomboid-like proteins in Apicomplexa: phylogeny and nomenclature

Autor: Timothy J. Dowse, Dominique Soldati

Publikováno v: Trends in Parasitology, Vol. 21, No 6 (2005) pp. 254-258

Rhomboids form a family of polytopic intramembrane serine proteases. In Toxoplasma gondii, an essential activity called microneme protein protease 1 (MPP1) cleaves secreted adhesive proteins within their transmembrane domains, at a site conserved in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedfa282a62b44e7b6a2d830a3bfa863
https://archive-ouverte.unige.ch/unige:78029

A family of transmembrane microneme proteins of Toxoplasma gondii contain EGF-like domains and function as escorters

Autor: Matthias Reiss, Nicola K. Viebig, James W. Ajioka, Markus Meissner, Dominique Soldati, Catherine Toursel, Vern B. Carruthers, Stanislas Tomavo

Publikováno v: Journal of Cell Science, Vol. 115, No Pt 3 (2002) pp. 563-74
Scopus-Elsevier

TgMIC6, TgMIC7, TgMIC8 and TgMIC9 are members of a novel family of transmembrane proteins localized in the micronemes of the protozoan parasite Toxoplasma gondii. These proteins contain multiple epidermal growth factor-like domains, a putative transm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc80bb2db4b7900e06521a4763edd065
https://pubmed.ncbi.nlm.nih.gov/11861763