Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction

Autor: Jackson, Verity A, Meijer, Dimphna H, Carrasquero, Maria, van Bezouwen, Laura S, Lowe, Edward D, Kleanthous, Colin, Janssen, Bert J C, Seiradake, Elena, Crystal and Structural Chemistry, Sub Crystal and Structural Chemistry, Sub Cryo - EM, Cryo-EM

Publikováno v: Nature Communications, 9(1). Nature Publishing Group

Teneurins are ancient cell-cell adhesion receptors that are vital for brain development and synapse organisation. They originated in early metazoan evolution through a horizontal gene transfer event when a bacterial YD-repeat toxin fused to a eukaryo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::94bbd0e4c3ed1fa7b313bd7d53ca0390
https://dspace.library.uu.nl/handle/1874/372861

Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction

Autor: Jackson, V, Meijer, D, Carrasquero, M, van Bezouwen, L, Lowe, E, Kleanthous, C, Janssen, B, Seiradake, E

Publikováno v: Nature Communications
'Nature Communications ', vol: 9, pages: 1079-1-1079-9 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)

Teneurins are ancient cell–cell adhesion receptors that are vital for brain development and synapse organisation. They originated in early metazoan evolution through a horizontal gene transfer event when a bacterial YD-repeat toxin fused to a eukar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::68ca554b61296bc8b0ec90b15b9fcc96

A 219-mer CHO-Expressing Receptor-Binding Domain of SARS-CoV S Protein Induces Potent Immune Responses and Protective Immunity

Autor: Yusen Zhou, Shibo Jiang, Lanying Du, Guangyu Zhao, Lin Li, CC Chan, Yuxian He, Bo-Jian Zheng

Publikováno v: Viral Immunology

Development of vaccines is essential for the prevention of future recurrences of severe acute respiratory syndrome (SARS), caused by the SARS coronavirus (SARS-CoV). The spike (S) protein, especially receptor-binding domain (RBD) of SARS-CoV, plays i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd4af15ce8d9371eb44bcbd9511d575

Cellular functions and X-ray structure of anthrolysin O, a cholesterol-dependent cytolysin secreted by Bacillus anthracis

Autor: Richard F. Rest, Raymond W. Bourdeau, Mitch L. Villereal, Enrico Malito, Wei-Jen Tang, Alexandre Chenal, Eugene B. Chang, Mark W. Musch, Elise M. Mosser, Brian L. Bishop

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (21), pp.14645-14656. ⟨10.1074/jbc.M807631200⟩
Journal of Biological Chemistry, 2009, 284 (21), pp.14645-14656. ⟨10.1074/jbc.M807631200⟩

International audience; Anthrolysin O (ALO) is a pore-forming, cholesterol-dependent cytolysin (CDC) secreted by Bacillus anthracis, the etiologic agent for anthrax. Growing evidence suggests the involvement of ALO in anthrax pathogenesis. Here, we s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1793df6fcebc99126dcd9422abef133f
https://hal-pasteur.archives-ouvertes.fr/pasteur-01540766

Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region

Autor: Xinming Tu, Christopher E. Yi, Michael Farzan, Agegnehu Gettie, Lei Ba, Chuan Qin, Wenjie Yu, Zhiwei Chen, Tian He, David D. Ho, Linqi Zhang, Fengwen Zhang, Kwok-Yung Yuen, Jian Yu, Qiang Wei, Hong Gao

Publikováno v: Journal of Virology

Immunization with a killed or inactivated viral vaccine provides significant protection in animals against challenge with certain corresponding pathogenic coronaviruses (CoVs). However, the promise of this approach in humans is hampered by serious co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41489b6012a6a9feb89ae2b075edb904
http://hdl.handle.net/10722/49158