Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Melwyn A. Abreo"'
Autor:
Mark J. Kurth, Melwyn A. Abreo
Publikováno v:
Tetrahedron. 46:5085-5092
Reacting vicinal epoxymesylates of general structure i with higher order and mixed higher order organocuprate reagents is shown to be very selective for attack at the least hindered epoxide center. The iterative application of this reaction - a seque
Autor:
James Arthur Thomson, Richard E. Showalter, J. Ernest Villafranca, Anna Tempczyk-Russell, Melwyn A. Abreo, Laura A. Pelletier, Charles R. Kissinger, Bin Li, Jerry J. Meng, Stephen Margosiak, Charles S. Agree, Robert M. Aust, Darin Vanderpool, Paul A. Rejto
Publikováno v:
Journal of molecular biology. 342(3)
The enzyme 17beta-hydroxysteroid dehydrogenase type 10 (HSD10), also known as amyloid beta-peptide-binding alcohol dehydrogenase (ABAD), has been implicated in the development of Alzheimer's disease. This protein, a member of the short-chain dehydrog
Autor:
Melwyn A. Abreo, Mark J. Kurth
Publikováno v:
ChemInform. 21
Reacting vicinal epoxymesylates of general structure i with higher order and mixed higher order organocuprate reagents is shown to be very selective for attack at the least hindered epoxide center. The iterative application of this reaction - a seque
Autor:
Mark J. Kurth, Melwyn A. Abreo
Publikováno v:
Tetrahedron Letters. 28:5631-5634
Vicinal epoxymesylates are shown to react regiospecifically with higher order organocuprates in a stepwise manner allowing for the isolation of either mono- or bis-adducts.