Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Melvys Valledor"'
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112686- (2023)
Summary: XIST RNA triggers chromosome-wide gene silencing and condenses an active chromosome into a Barr body. Here, we use inducible human XIST to examine early steps in the process, showing that XIST modifies cytoarchitecture before widespread gene
Externí odkaz:
https://doaj.org/article/7ac131bf9fd54ef19ba4a7259ef1c7ea
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0200955 (2018)
Recombineering has transformed functional genomic analysis. Genome modification by recombineering using the phage lambda Red homologous recombination protein Beta in Escherichia coli has approached 100% efficiency. While highly efficient in E. coli,
Externí odkaz:
https://doaj.org/article/b96ca7e7fbbe4cbb8e82d7ff82f66de0
SUMMARYXIST RNA triggers gene silencing chromosome-wide and transforms a euchromatic chromosome into a condensed Barr body. XIST is heavily studied in mouse ES cells, but here an inducible iPSC system allows analysis of initial steps in human chromos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7480559f8bbbb76596d4778885485229
https://doi.org/10.1101/2022.02.04.479153
https://doi.org/10.1101/2022.02.04.479153
Publikováno v:
IUBMB Life. 64:684-689
In vivo site-directed mutagenesis by single-stranded deoxyribonucleic acid recombineering is a facile method to change the color of fluorescent proteins (FPs) without cloning. Two different starting alleles of GFP were targeted for mutagenesis: gfpmu
Autor:
Darryl Horn, Ileana C. Soto, Flavia Fontanesi, Melvys Valledor, Antoni Barrientos, Rajiv Singh
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (11):1776-1786
The mitochondrial F1F0-ATP synthase or ATPase is a key enzyme for aerobic energy production in eukaryotic cells. Mutations in ATPase structural and assembly genes are the primary cause of severe human encephalomyopathies, frequently associated with a