Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Melvyn S, Soloff"'
Autor:
Mala Sinha, Susan Stamnes, Michael G. Izban, Sarah K. England, Melvyn S. Soloff, Bruce A. Luxon, Yow Jiun Jeng
Publikováno v:
Reproductive Sciences. 18:781-797
An important action of progesterone during pregnancy is to maintain the uterus in a quiescent state and thereby prevent preterm labor. The causes of preterm labor are not well understood, so progesterone action on the myometrium can provide clues abo
Autor:
Yow-Jiun Jeng, Melvyn S. Soloff
Publikováno v:
Biology of Reproduction. 81:473-479
Oxytocin (OXT) is a potent stimulator of prostaglandin E 2 (PGE 2 ) synthesis by rabbit amnion cells obtained near the end of pregnancy. Coincident with a marked increase in sensitivity of PGE 2 synthesis to OXT, the concentration of OXT receptors (O
Publikováno v:
Endocrinology. 145:1248-1254
The specific binding of transcription factors to DNA has been shown to be inhibited by chromatin structure and increased by cooperative interactions with other proteins. Consequently, in situ analysis using chromatin immunoprecipitation offers the mo
Autor:
Mary Hunzicker-Dunn, Garland D. Anderson, Melvyn S. Soloff, Thomas G. Wood, Sangwan Gal, Carl A. Peters, Sarasija Hoare
Publikováno v:
Gene. 323:149-155
Relaxin, a hormone in the insulin superfamily, is synthesized by the corpus luteum of the rat ovary. Expression of relaxin precursor mRNA in rats is sharply induced after day 10 of pregnancy and plateaus on days 15 to 20 (parturition occurs on day 23
Autor:
Darryl L, Hadsell, Sharon, Bonnette, Jessy, George, Daniel, Torres, Yann, Klimentidis, Yann, Klementidis, Shan, Gao, Peter M, Haney, Joan, Summy-Long, Melvyn S, Soloff, Albert F, Parlow, Mario, Sirito, Michele, Sawadogo
Publikováno v:
Molecular Endocrinology. 17:2251-2267
Previous studies have suggested that upstream stimulatory factors (USFs) regulate genes involved with cell cycle progression. Because of the relationship of USFs to an important oncogene in breast cancer, c-myc, we chose to determine the importance o
Publikováno v:
Endocrinology. 144:61-68
Oxytocin receptor (OTR) expression in human myometrium increases over 150-fold from the beginning of pregnancy to the end. In the present studies, we examined potential mechanisms of OTR up-regulation, using myometrial cells in primary culture from w
Publikováno v:
Biology of Reproduction. 66:1230-1236
Although oxytocin and its receptor have been identified in human ovary, its regulatory role in granulosa cell or corpus luteum function has not been clearly defined. To better understand oxytocin action in the human ovary, we have characterized the e
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 282:E580-E584
Regulators of G protein signaling (RGS proteins) interact with Gαq and Gαi and accelerate GTPase activity. These proteins have been characterized only within the past few years, so our understanding of their importance is still preliminary. We exam
Autor:
Melvyn S. Soloff, Kirk L. Ives, Zuzana Strakova, Yow-Jiun Jeng, Mark R. Hellmich, Daniel Liebenthal
Publikováno v:
Endocrinology. 141:4136-4145
The up-regulation of oxytocin (OT) receptors in rabbit amnion at the end of gestation is associated with a large increase in the ability of OT to stimulate PGE2 synthesis. The purpose of these investigations was to determine what other factors contri
Publikováno v:
Experimental Physiology. 85:51s-58s
A major action of oxytocin is to stimulate prostaglandin production in reproductive tissues. The two major enzyme systems involved are cytosolic phospholipase A2 (cPLA2), which catalyses the formation of arachidonic acid from membrane glycerophosphol