Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Melvyn Lieberman"'
Publikováno v:
Cell Biology International. 24:713-721
Cultured chick embryo cardiac myocytes submitted to a 180 mOsm/kg hyposmotic solution swell present a regulatory volume decrease (RVD). This RVD is mediated by a Ca(2+)influx followed by a 40% loss of total taurine content accompanied by the loss of
Publikováno v:
Molecular and Cellular Biochemistry. 210:173-183
Previous studies in chick embryo cardiac myocytes have shown that the inhibition of Na+/K+-ATPase with ouabain induces cell shrinkage in an isosmotic environment (290 mOsm). The same inhibition produces an enhanced RVD (regulatory volume decrease) in
Autor:
Phillip G. Nelson, Melvyn Lieberman
The tissue culture approach to the study of membrane properties of excitable cells has progressed beyond the technical problems of culture methodology. Recent developments have fostered substantive contributions in research con cerned with the phys
Autor:
Shi Liu, Melvyn Lieberman
Publikováno v:
Cardiovascular Research. 28:1629-1634
Objective: The aim was to demonstrate that removal of extracellular sodium (Na+o), a manoeuvre known to increase intracellular calcium (Ca2+i), can activate a chloride ion conductance in cultured embryonic chick heart cells. Methods: Intracellular ch
Publikováno v:
Journal of Molecular and Cellular Cardiology. 26:797-808
Calcium-free incubation followed by exposure to calcium damages naturally occurring cardiac muscle preparations irreversibly. Whether the observed calcium overload during calcium repletion is a primary cause for, or a secondary consequence of, sarcol
Publikováno v:
The Journal of Physiology. 472:801-820
1. Cultured chick heart cells challenged by hyposmotic stress underwent regulatory volume decrease (RVD) that was attenuated by prior depletion of intracellular chloride. 2. During hyposmotic swelling, cell aggregates experienced an initial increase
Autor:
Melvyn Lieberman, David Piwnica-Worms, J. Kronauge, Daniel Hockett, Ann LeFurgey, Peter Ingram, Mark Backus
Publikováno v:
American Journal of Physiology-Cell Physiology. 265:C178-C187
Hexakis (2-methoxyisobutylisonitrile) technetium-99m (99mTc-MIBI) is a gamma-emitting radiopharmaceutical probe currently in clinical use to evaluate myocardial perfusion. Biochemical and cellular pharmacological studies have suggested that Tc-MIBI,
Publikováno v:
Basic Research in Cardiology. 88:411-420
Myocardial cell swelling occurs in ischemia and in reperfusion injury before the onset of irreversible injury. Swelling has been attributed to failure of the Na+/K+ pump and the accumulation of intracellular Na+. To evaluate the role of the pump-leak
Publikováno v:
Journal of Microscopy. 168:259-273
SUMMARY A new method has been developed which allows quick-freezing in situ of primary, cardiac cell cultures grown to confluence on gas-permeable membranes (Petriperm dishes). Small pieces of the growth substratum, with rhythmically beating myocardi
Publikováno v:
American Journal of Physiology-Cell Physiology. 262:C1024-C1030
To assess the role of pH in cellular Mg homeostasis, cytosolic pH (pHi) was manipulated by the NH4Cl prepulse technique; pHi, cytosolic Mg2+ (Mgi), and cytosolic Ca2+ (Cai) were measured fluorometrically in single cultured embryonic chicken heart cel