Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Melvin R. Dickerson"'
Autor:
Brian Nichelson, Mark G. Vartanian, Charles Taylor, Susan M. Lotarski, Nancy Sue Barta, Sean D. Donevan, Sian E. Gibbons, Norman L. Colbry, Zhu Zhijian, Melvin R. Dickerson, Paul Galatsis, Russell J. DeOrazio, Jacob Bradley Schwarz, Kristin Knapp Lin, Zheng Li, Andrew John Thorpe, Jack J. Kinsora, Raymond Andrew Hudack, David J. Wustrow, David D. Manning, Ayman El-Kattan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:3559-3563
Several beta-amino tetrazole analogs of gabapentin 1 and pregabalin 2 were prepared by one of two convergent, highly efficient routes, and their affinity for the alpha(2)-delta protein examined. Two select compounds with potent affinity for alpha(2)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71639ec10a452e24f369e2dc36c1c1f
https://doi.org/10.1016/j.bmcl.2006.03.083
https://doi.org/10.1016/j.bmcl.2006.03.083
Autor:
M. Vandorf, Bradley William Caprathe, Katharyn Spiegel, James S. Marks, James H. Fergus, T.W. Hepburn, Melvin R. Dickerson, D. Agrafiotis, Robert E. Davis, D.M. Wieland, Juan C. Jaen
Publikováno v:
Biochemical and Biophysical Research Communications. 217:488-494
Nerve growth factor is a peptide that supports the survival and differentiation of discrete neuronal populations in the peripheral and central nervous systems. NGF binds to both trkA, a tyrosine kinase receptor, and to the p75 nerve growth factor rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3155f0543046d56fd9edb44979eca0
https://doi.org/10.1006/bbrc.1995.2802
https://doi.org/10.1006/bbrc.1995.2802
Autor:
Bradley William Caprathe, Katharyn Spiegel, Juan C. Jaen, James S. Marks, Ruth A. Bucsh, Edgardo Laborde, James H. Fergus, Robert E. Davis, Roderick Joseph Sorenson, Melvin R. Dickerson
Publikováno v:
ChemInform. 27
The ability of a series of substituted kynurenic acids, thienopyridinonecarboxylic acids, and related compounds to inhibit the binding of nerve growth factor (NGF) to the p75 NGF receptor (NGFR) was evaluated in a radioligand binding assay that utili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3c0582d0878c8086fcb5c7b30d17825
https://doi.org/10.1002/chin.199610201
https://doi.org/10.1002/chin.199610201
Autor:
Susan M. Lotarski, David J. Wustrow, Melvin R. Dickerson, Norman L. Colbry, Mark L. Weber, Shelley Rene Graham, Sian E. Gibbons, Ti-Zhi Su, Schwarz Jacob Bradley, Jack J. Kinsora, Ayman El-Kattan, Mark G. Vartanian, Andrew J. Thorpe, Van-Duc Le, Peter R. Guzzo, Charles Price Taylor, Sean D. Donevan, Zheng Li
Publikováno v:
Journal of medicinal chemistry. 48(8)
As part of a program aimed at generating compounds with affinity for the alpha(2)-delta subunit of voltage-gated calcium channels, several novel beta-amino acids were prepared using an efficient nitroalkane-mediated cyclopropanation as a key step. De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16b56d1bccad3bb7ecbbe1836620fa4
https://pubmed.ncbi.nlm.nih.gov/15828841
https://pubmed.ncbi.nlm.nih.gov/15828841
Autor:
James H. Fergus, Robert E. Davis, Katharyn Spiegel, Bradley William Caprathe, Melvin R. Dickerson, Roderick Joseph Sorenson, James S. Marks, Juan C. Jaen, Ruth A. Bucsh, Edgardo Laborde
Publikováno v:
Journal of medicinal chemistry. 38(22)
The ability of a series of substituted kynurenic acids, thienopyridinonecarboxylic acids, and related compounds to inhibit the binding of nerve growth factor (NGF) to the p75 NGF receptor (NGFR) was evaluated in a radioligand binding assay that utili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4669698aa7c133cf5fa19f3f4cc51d51
https://pubmed.ncbi.nlm.nih.gov/7473570
https://pubmed.ncbi.nlm.nih.gov/7473570