Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Melvin Lyon"'
1
Investigations of fetal development models for prenatal drug exposure and schizophrenia. Prenatald-amphetamine effects upon early and late juvenile behavior in the rat
Autor: William O. McClure, Melvin Lyon
Publikováno v: Psychopharmacology. 116:226-236
Recent evidence suggests that mid-pregnancy is a critical period for production of fetal abnormalities that cause behavioral and neuropathological changes in adult offspring. The present experiments provide an animal model of these effects by treatin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b325cc6bf02dcaff7a8f3a0c8313af15
https://doi.org/10.1007/bf02245066
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2
The importance of temporal structure in analyzing schizophrenic behavior: some theoretical and diagnostic implications
Autor: Nancy Lyon, Melvin Lyon, Magnus S. Magnusson
Publikováno v: Schizophrenia Research. 13:45-56
THEME, a new method for analyzing the temporal structure of responding on a two-choice task, is described. This method reveals the time relationships (temporal patterns) between all response events, even those not occurring in direct sequence. It sel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c1dc1f43bd1b95c9f5861ac812c0cc
https://doi.org/10.1016/0920-9964(94)90059-0
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3
Temporal patterns of self-injurious behavior correlate with stress hormone levels in the developmentally disabled
Autor: Aaron S. Kemp, Paul Fillmore, Paul E. Touchette, Aleksandra Chicz-DeMet, Curt A. Sandman, Mohammed R. Lenjavi, Melvin Lyon
Publikováno v: Kemp, Aaron S; Fillmore, Paul T; Lenjavi, Mohammed R; Lyon, Melvin; Chicz-Demet, Aleksandra; Touchette, Paul E; et al.(2008). Temporal patterns of self-injurious behavior correlate with stress hormone levels in the developmentally disabled. Psychiatry Research, 157(1-3), 181-189. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/76f3812t
While the origins and developmental course of self-injurious behavior (SIB) remain relatively unknown, recent studies suggest a biological imbalance may potentiate or provoke the contagious recurrence of SIB patterns in individuals with severe develo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c16223f6501b831fc2a159c8387603
http://www.escholarship.org/uc/item/76f3812t
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4
Localized 7Li MR spectroscopy: in vivo brain and serum concentrations in the rat
Autor: John M. Pearce, Richard A. Komoroski, Melvin Lyon
Publikováno v: Magnetic resonance in medicine. 52(5)
The brain concentration of lithium (Li) in treated rats was measured using a recently developed method based on in vivo 7Li PRESS localized MRS. Comparison was made to the corresponding serum concentration at two treatment durations. The brain and se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4269f8b1d67cfcb06258f77c2a06b5f2
https://pubmed.ncbi.nlm.nih.gov/15508147
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5
Pharmacokinetics of lithium in rat brain regions by spectroscopic imaging
Autor: Jiaxiong Pi, Elzbieta Ripp, Subbaraya Ramaprasad, Melvin Lyon
Publikováno v: Magnetic resonance imaging. 23(8)
Lithium (Li) and its salts have been demonstrated to be the most effective drug in both acute and prophylactic treatment of bipolar disorder. The exact molecular mechanisms and particular target regions accounting for its mood-stabilizing effect rema
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793922ae82a09f621f201f25c57b2fc2
https://pubmed.ncbi.nlm.nih.gov/16275424
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6
Very mild stress of pregnant rats reduces volume and cell number in nucleus accumbens of adult offspring: some parallels to schizophrenia
Autor: William O. McClure, Melvin Lyon, Armine Ishtoyan
Publikováno v: Brain research. Developmental brain research. 149(1)
Pregnant rats subjected to very mild stress give birth to pups who, when examined as adults, exhibited behavioral and anatomical anomalies that resemble some aspects of schizophrenia. The nucleus accumbens (NAcc) is reduced in volume by 20.7 +/- 3.4%
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1cc9a09e120f20ff384a62a881f711
https://pubmed.ncbi.nlm.nih.gov/15013625
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9
Increased temporal patterns in choice responding and altered cognitive processes in schizophrenia and mania
Autor: Melvin Lyon, Aaron S. Kemp
Publikováno v: Psychopharmacology. 172(2)
The THEME method for measuring time-determined patterns (T-patterns) in behavior has been suggested as a new, more objective method for assessing cognitive disturbances in schizophrenia.THEME was used to compare responses of schizophrenic patients wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8728065fb6ac2decfed9d16c5247080
https://pubmed.ncbi.nlm.nih.gov/14576973
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10
Fetal Developmental Animal Model of Schizophrenia with Dopamine, Acetylcholine, and Nitric Oxide Perspectives
Autor: Melvin Lyon, William O. McClure
Publikováno v: Neural Development and Schizophrenia ISBN: 9781461358039
The interest in finding an animal model of schizophrenia began with the report of Mednick et al. (1988), that schizophrenia risk for the offspring was doubled by maternal exposure to a viral epidemic in the second trimester of pregnancy (Barr et al.,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95f3071c7b8d3796f2cc39c837925306
https://doi.org/10.1007/978-1-4615-1955-3_7
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