Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Melvin Levine"'
Publikováno v:
Hypertension. 6:374-382
Spleen cells from mice immunized with partially purified hog kidney renin were fused with mouse myeloma cells to produce a stable monoclonal hybridoma cell line that synthesizes an antibody against renin. A single monoclonal antibody was chosen for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b8ad0bcd8ff1b1dd9ee64895310d97
https://doi.org/10.1161/01.hyp.6.3.374
https://doi.org/10.1161/01.hyp.6.3.374
Publikováno v:
Circulation Research. 34:824-827
Two dipeptides, phenylalanylarginine (Phe-Arg) and serylproline (Ser-Pro), are released sequentially from bradykinin by angiotensin-converting enzyme purified from hog lungs; chloride increases the rate of release of both dipeptides. Using an automat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad1b7a6af4c7d6f59dfa831ce5c8782
https://doi.org/10.1161/01.res.34.6.824
https://doi.org/10.1161/01.res.34.6.824
Publikováno v:
The American Journal of Medicine. 60:737-748
The renin-angiotensin system has an important role in maintaining elevated blood pressure levels in certain forms of experimental and human hypertension. Renin, an enzyme produced by the juxtaglomerular cells of the kidney, acts on a protein substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a39cedc4f83f60eb8b2130ae90bc64d
https://doi.org/10.1016/0002-9343(76)90888-3
https://doi.org/10.1016/0002-9343(76)90888-3
Publikováno v:
Analytical Biochemistry. 87:11-18
Renin substrate, angiotensinogen, has been purified from human plasma by methods which permit the processing of large amounts of outdated bank blood. The purified protein is homogeneous by disc gel electrophoresis at pH 9.5. The specific activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00ca8a3959a3266590b804d50359bce
https://doi.org/10.1016/0003-2697(78)90563-8
https://doi.org/10.1016/0003-2697(78)90563-8
Publikováno v:
Circulation Research. 37:715-724
An investigation into the mechanism that sustains the blood pressure in chronic one-kidney hypertension in rabbits was made using passive and active immunization with hog kidney extracts containing renin and with angiotensin antagonists. Seven hypert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7f8fd155aec8b645f8a9f8215d3700
https://doi.org/10.1161/01.res.37.6.715
https://doi.org/10.1161/01.res.37.6.715
Publikováno v:
Circulation Research. 39:400-406
The arterial pressure of rabbits with chronic one-kidney hypertension can be lowered to normotensive levels by direct immunization with preparations made from the cortex of hog kidneys. Hypertensive rabbits that are immunized with large amounts of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3bcadfba12600e81f18bd82997b3f5
https://doi.org/10.1161/01.res.39.3.400
https://doi.org/10.1161/01.res.39.3.400
Autor:
Melvin Levine, Harold Tarver
Publikováno v:
Journal of Biological Chemistry. 184:427-436
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6447df26142865dddb54f6fdc05dd516
https://doi.org/10.1016/s0021-9258(19)50971-1
https://doi.org/10.1016/s0021-9258(19)50971-1
Autor:
John V. Fopeano, Melvin Levine
Publikováno v:
Journal of Biological Chemistry. 202:597-605
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d452856b06276bb1b914d01aace6020
https://doi.org/10.1016/s0021-9258(18)66173-3
https://doi.org/10.1016/s0021-9258(18)66173-3
Publikováno v:
Analytical Biochemistry. 33:102-113
An automated, continuous-flow method for measuring angiotensin converting enzyme activity has been developed employing the ninhydrin reaction. The method measures the new free amino group produced when angiotensin I is hydrolyzed to angiotensin II an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12124e7f393427a0e5e3c3de3cf90d4
https://doi.org/10.1016/0003-2697(70)90443-4
https://doi.org/10.1016/0003-2697(70)90443-4
Publikováno v:
Circulation Research. 31:356-366
Angiotensin-converting enzyme was purified 1500-fold from a homogenate of hog lungs. The purification procedure included fractionation with ammonium sulfate, inactivation of contaminating enzymes at pH 4.7, batch treatment with CM-cellulose, and chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dccfa44d55a27885e57e3ab06dbfa166
https://doi.org/10.1161/01.res.31.3.356
https://doi.org/10.1161/01.res.31.3.356