Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Melvin Khee-Shing Leow"'
Autor:
Xinpeng Loh, Lijuan Sun, John Carson Allen, Hui Jen Goh, Siew Ching Kong, Weiting Huang, Cherlyn Ding, Nabil Bosco, Leonie Egli, Lucas Actis-Goretta, Faidon Magkos, Fabrizio Arigoni, Khung Keong Yeo, Melvin Khee-Shing Leow
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The prediction utility of Framingham Risk Score in populations with low conventional cardiovascular risk burden is limited, particularly among women. Gender-specific markers to predict cardiovascular risk in overtly healthy people are lackin
Externí odkaz:
https://doaj.org/article/247bd7dcc8444ea18a457c263b5fd7e8
Autor:
Lijuan Sun, Hui Jen Goh, Sanjay Verma, Priya Govindharajulu, Suresh Anand Sadananthan, Navin Michael, Christiani Jeyakumar Henry, Julian Park-Nam Goh, S. Sendhil Velan, Melvin Khee-Shing Leow
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Both hyperthyroidism and elevated plasma branched chain amino acids (BCAA) are associated with insulin resistance. BCAA utilization and clearance relative to thyroid status changes remains unclear. We investigate amino acids changes, specifi
Externí odkaz:
https://doaj.org/article/35d28230744c4c97a89b4893b52b8077
Autor:
See Ling Loy, Jinjie Lin, Yin Bun Cheung, Aravind Venkatesh Sreedharan, Xinyi Chin, Keith M. Godfrey, Kok Hian Tan, Lynette Pei-Chi Shek, Yap Seng Chong, Melvin Khee-Shing Leow, Chin Meng Khoo, Yung Seng Lee, Shiao-Yng Chan, Ngee Lek, Jerry Kok Yen Chan, Fabian Yap
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Abnormalities of red blood cell (RBC) indices may affect glycated haemoglobin (HbA1c) levels. We assessed the influence of haemoglobin (Hb) and mean corpuscular volume (MCV) on the performance of HbA1c in detecting dysglycaemia among reprodu
Externí odkaz:
https://doaj.org/article/a4138a5b3ce64e0a917507d060c1dc76
Autor:
Benjamin Huang, Weiting Huang, John Carson Allen, Lijuan Sun, Hui Jen Goh, Siew Ching Kong, Dewaine Lee, Cherlyn Ding, Nabil Bosco, Leonie Egli, Lucas Actis-Goretta, Faidon Magkos, Fabrizio Arigoni, Melvin Khee-Shing Leow, Swee Yaw Tan, Khung Keong Yeo
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
BackgroundSubclinical atherosclerosis can be present in individuals with an optimal cardiovascular risk factor profile. Traditional risk scores such as the Framingham risk score do not adequately capture risk stratification in low-risk individuals. T
Externí odkaz:
https://doaj.org/article/1307fa9cc3224012ac523a27643da669
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
It is well established that thyroid dysfunction is linked to an increased risk of cardiovascular morbidity and mortality. The pleiotropic action of thyroid hormones strongly impacts the cardiovascular system and affects both the generation of the nor
Externí odkaz:
https://doaj.org/article/31caa11ef6194e2a9e70e1180a3880c4
Autor:
Anne H. Y. Chu, Izzuddin M. Aris, Sharon Ng, See Ling Loy, Jonathan Y Bernard, Mya Thway Tint, Wen Lun Yuan, Keith M. Godfrey, Jerry Kok Yen Chan, Lynette Pei-Chi Shek, Yap Seng Chong, Kok Hian Tan, Seng Bin Ang, Heng Hao Tan, Bernard S. M. Chern, Fabian Yap, Yung Seng Lee, Ngee Lek, Melvin Khee-Shing Leow, Chin Meng Khoo, Shiao-Yng Chan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract We investigated whether adding anthropometric measures to HbA1c would have stronger discriminative ability over HbA1c alone in detecting dysglycemia (diabetes and prediabetes) among Asian women trying to conceive. Among 971 Singaporean women
Externí odkaz:
https://doaj.org/article/8fa5d7e53b5c4646be05135981dec54a
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
Background: Devising a program to increase physical activity (PA)/exercise behavior in patients with type 2 diabetes mellitus (T2DM) can meet with limited effectiveness in real-world settings because of the variety of barriers to PA/exercise that ind
Externí odkaz:
https://doaj.org/article/1643248814b14a679ba8fa9a0f1c2a74
Autor:
Cherlyn Ding, Leonie Egli, Nabil Bosco, Lijuan Sun, Hui Jen Goh, Khung Keong Yeo, Jonathan Jiunn Liang Yap, Lucas Actis-Goretta, Melvin Khee-Shing Leow, Faidon Magkos
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
Background: Plasma branched-chain amino acids (BCAA) are consistently elevated in subjects with obesity and type 2 diabetes (T2DM) and correlate with insulin resistance. The association of BCAA with insulin secretion and clearance rates has not been
Externí odkaz:
https://doaj.org/article/e2aed53bece24f7884b11461fc794d5b
Autor:
Chunming Ding, Yen Ching Lim, Sook Yoong Chia, Arcinas Camille Esther Walet, Shaohai Xu, Kinyui Alice Lo, Yanling Zhao, Dewen Zhu, Zhihui Shan, Qingfeng Chen, Melvin Khee-Shing Leow, Dan Xu, Lei Sun
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Long non-coding RNAs are known to regulate mouse white adipose tissue development and brown adipose tissue program expression. Here, the authors construct a roadmap for human long non-coding RNAs expressed in fetal brown adipose tissue, adult omental
Externí odkaz:
https://doaj.org/article/f9650c4841264881a512ef772db8f1a0
Publikováno v:
Scientific Phone Apps and Mobile Devices, Vol 3, Iss 1, Pp 1-5 (2017)
Abstract Thyroid-SPOT is a mobile application that allows users to be able to analyse thyroid function tests laboratory reports by computing the homeostatic euthyroid set point based on regressing thyroid function data according to a patented algorit
Externí odkaz:
https://doaj.org/article/df28926ab535456c8ca122b9db0c1593