Zobrazeno 1 - 10
of 4 864
pro vyhledávání: '"Melvin E"'
Autor:
Marjory Moreau, Liam Simms, Melvin E. Andersen, Edgar Trelles Sticken, Roman Wieczorek, Sarah Jean Pour, Fiona Chapman, Karin Roewer, Sandra Otte, Jeffrey Fisher, Matthew Stevenson
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
With the use of in vitro new approach methodologies (NAMs) for the assessment of non-combustible next-generation nicotine delivery products, new extrapolation methods will also be required to interpret and contextualize the physiological relevance of
Externí odkaz:
https://doaj.org/article/06e7c45c8815464bb61eca7e8d431b5c
Autor:
Juan M. Barajas, Masayuki Umeda, Lisett Contreras, Mahsa Khanlari, Tamara Westover, Michael P. Walsh, Emily Xiong, Chenchen Yang, Brittney Otero, Marc Arribas-Layton, Sherif Abdelhamed, Guangchun Song, Xiaotu Ma, Melvin E. Thomas 3rd, Jing Ma, Jeffery M. Klco
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Recent genomic studies in adult and pediatric acute myeloid leukemia (AML) demonstrated recurrent in-frame tandem duplications (TD) in exon 13 of upstream binding transcription factor (UBTF). These alterations, which account for ~4.3% of AMLs in chil
Externí odkaz:
https://doaj.org/article/c0412839c08c4746996ccbccb8f2f704
Autor:
Sonya R. Kennedy, Maxime Lafond, Kevin J. Haworth, Daniel Suarez Escudero, Dan Ionascu, Brion Frierson, Shaoling Huang, Melvin E. Klegerman, Tao Peng, David D. McPherson, Curtis Genstler, Christy K. Holland
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Ultrasound-enhanced delivery of therapeutic-loaded echogenic liposomes is under development for vascular applications using the EkoSonic Endovascular System. In this study, fibrin-targeted echogenic liposomes loaded with an anti-inflammatory
Externí odkaz:
https://doaj.org/article/47b03a8ce6094d39a359e684fdee0ea0
Autor:
Anderson C. Armstrong, Rodrigo Cerci, Matthew B. Matheson, Tiago Magalhães, Satoru Kishi, Jeff Brinker, Melvin E. Clouse, Carlos E. Rochitte, Christopher Cox, João A. C. Lima, Armin Arbab-Zadeh
Publikováno v:
Arquivos Brasileiros de Cardiologia, Vol 120, Iss 3 (2023)
Resumo Fundamento A avaliação do Escore de Cálcio Coronariano (ECC) pode ser realizada por tomografia computadorizada sem contraste para prever eventos cardiovasculares, mas tem menor valor na estratificação de risco em pacientes sintomáticos.
Externí odkaz:
https://doaj.org/article/2f4cc2baa9474f22acf6fdb54c34d54a
Autor:
Sherif Abdelhamed, Melvin E. Thomas III, Tamara Westover, Masayuki Umeda, Emily Xiong, Chandra Rolle, Michael P. Walsh, Huiyun Wu, Jason R. Schwartz, Virginia Valentine, Marcus Valentine, Stanley Pounds, Jing Ma, Laura J. Janke, Jeffery M. Klco
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 21 (2022)
SAMD9 and SAMD9L germline mutations have recently emerged as a new class of predispositions to pediatric myeloid neoplasms. Patients commonly have impaired hematopoiesis, hypocellular marrows, and a greater risk of developing clonal chromosome 7 dele
Externí odkaz:
https://doaj.org/article/8e1fedf5f7604a43996d6f336e9bfb71
Autor:
Chantel I. Nicolas, Matthew W. Linakis, Melyssa S. Minto, Kamel Mansouri, Rebecca A. Clewell, Miyoung Yoon, John F. Wambaugh, Grace Patlewicz, Patrick D. McMullen, Melvin E. Andersen, Harvey J. Clewell III
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Current computational technologies hold promise for prioritizing the testing of the thousands of chemicals in commerce. Here, a case study is presented demonstrating comparative risk-prioritization approaches based on the ratio of surrogate hazard an
Externí odkaz:
https://doaj.org/article/c77f706ac85c49c3bc5d018511b024a1
Autor:
Melvin E. Klegerman, Tao Peng, Shao-Ling Huang, Brion Frierson, Melanie R. Moody, Hyunggun Kim, David D. McPherson
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2288 (2023)
We have conducted a stability study of a complex liposomal pharmaceutical product, Atheroglitatide (AGT), stored at three temperatures, 4, 24, and 37 °C, for up to six months. The six parameters measured were functions of liposomal integrity (size a
Externí odkaz:
https://doaj.org/article/640149126785435a967db9f6ded1c6b9
Autor:
Patrick H. Kee, MD, PhD, Melanie R. Moody, BSc, Shao-Ling Huang, PhD, Hyunggun Kim, PhD, Xing Yin, MD, PhD, Tao Peng, MD, Susan T. Laing, MD, Melvin E. Klegerman, PhD, Mohammad H. Rahbar, PhD, Deborah Vela, MD, Curtis Genstler, MD, PhD, Kevin J. Haworth, PhD, Christy K. Holland, PhD, David D. McPherson, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 1, Pp 1-11 (2020)
Summary: Late in-stent restenosis remains a significant problem. Bare-metal stents were implanted into peripheral arteries in miniature swine, followed by direct intra-arterial infusion of nitric oxide–loaded echogenic liposomes (ELIPs) and anti–
Externí odkaz:
https://doaj.org/article/6799d85165144a17bc107c5ee232352d
Autor:
Michael B. Black, Melvin E. Andersen, Salil N. Pendse, Susan J. Borghoff, Michael Streicker, Patrick D. McMullen
Publikováno v:
Data in Brief, Vol 38, Iss , Pp 107420- (2021)
The National Toxicology Program (NTP) reported that chronic exposure to varying dietary concentrations of 4-methylimidazole (4-MeI) increased lung tumors in female and male mice [1]. In this study, mice (male and female B6C3F1 mice) were either admin
Externí odkaz:
https://doaj.org/article/14f8cca609cc494895eaded385e8c96a
Autor:
Gustavo Romero-Velez, Jody M. Kaban, Edward Chao, Erin R. Lewis, Melvin E. Stone, Jr, Sheldon Teperman, Srinivas H. Reddy
Publikováno v:
Trauma Case Reports, Vol 28, Iss , Pp 100324- (2020)
Penetrating cardiac injuries have a pre-hospital mortality of 94% with a subsequent in-hospital mortality of 50% among initial survivors (Leite et al., 2017 [1]). The Western Trauma Association (WTA) guidelines recommend resuscitative thoracotomy (RT
Externí odkaz:
https://doaj.org/article/265e1a0744104b91af13e64ca5254ae1