Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Melvin D.S. Wong"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 101:3794-3802
A recent study suggested that urinary haptoglobin may be a novel biomarker to improve predictive performance of albuminuria in type 2 diabetes mellitus (T2DM). However, the finding has not been externally validated.The objective of the study was to e
Autor:
Subramaniam Tavintharan, Melvin D.S. Wong, Lee Ying Yeoh, Wern Ee Tang, Simon Biing Ming Lee, Xiao Wei Ng, Su Chi Lim, Benjamin Chih Chiang Lam, Chang Su, Chee Fang Sum, Mei Chung Moh
Publikováno v:
Diabetes and Vascular Disease Research. 12:111-118
Cardiovascular disease is the leading cause of morbidity and mortality in type 2 diabetes mellitus. We evaluated the predictive ability of the recently developed body adiposity index for aortic stiffness, an intermediate endpoint of cardiovascular di
Autor:
Jianjun Liu, Subramaniam Tavintharan, Melvin D.S. Wong, Nils G. Morgenthaler, Chee Fang Sum, Sylvia Liu, Su Chi Lim
Publikováno v:
Atherosclerosis. 233:415-418
Objectives To study the relationship between plasma soluble klotho (sKlotho) and pro-endothelin-1 (proET-1) in patients with type 2 diabetes (T2DM). Subjects and methods In this cross-sectional study, we recruited 175 T2DM subjects and 56 non-diabeti
Autor:
Su Chi Lim, Clara Si Hua Tan, Sylvia Liu, Chee Fang Sum, Jianjun Liu, Subramaniam Tavintharan, Melvin D.S. Wong
Publikováno v:
Journal of Diabetes and its Complications. 28:208-213
Aims Chronic kidney disease (CKD) secondary to type 2 diabetes mellitus (T2DM) is associated with multifaceted energy dysmetabolism. We aim to study the relationship between renal function, body composition and irisin, the recently identified myokine
Autor:
W. C. Toy, S. Tavintharan, Jianjun Liu, Melvin D.S. Wong, Chee Fang Sum, Su Chi Lim, Chen S. Tan, M. S. Wong
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 121:329-333
Accumulating data suggest that bone plays a role in energy metabolism through decarboxylation of osteocalcin. Thus, we aimed to study the association of circulating under--carboxylated osteocalcin (UC-OCN) and car-boxylated osteocalcin (C-OCN) with m
Autor:
Melvin D.S. Wong, Wan Ching Toy, Su Chi Lim, Subramaniam Tavintharan, Chee Fang Sum, Xiao Wei Ng, Jianjun Liu, Clara Si Hua Tan, Sylvia Liu
Publikováno v:
Journal of diabetes and its complications. 27(4)
Irisin is a novel myokine secreted in response to PPAR-γ co-activator-1α (PGC-1α) activation. Earlier studies suggested that PGC-1α expression and activity were lower in myocytes in type 2 diabetes mellitus (T2DM). Therefore, we hypothesize that
Autor:
Lee Ying Yeoh, Chee Fang Sum, Kiat Mun Serena Low, Jeevith Babitha, Clara Si Hua Tan, Chang Su, Melvin D.S. Wong, Sylvia Liu, Xiao Zhang, Subramaniam Tavintharan, Su Chi Lim, Rajkumar Dorajoo, Xiao Wei Ng, Wern Ee Tang, Jianjun Liu, Su Fen Ang, Na Li, Ling Wang, Amy Ou Yao, Shiyi Zhou, Simon Biing Ming Lee, Sharon Fun
Publikováno v:
Nephrology Dialysis Transplantation. :gfw263
Background The soluble receptor for advanced glycation end products (sRAGE) has been shown to play an important role in diabetic complications. We conducted genome-wide association study (GWAS) of sRAGE in Asian type 2 diabetes mellitus (T2DM) patien