Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Melvin D. Yahr"'
Publikováno v:
Parkinsonism & Related Disorders. 11:151-155
The aim of the study was to investigate the relationship between dyskinesias and motor fluctuations in patients with Parkinson's disease on l-dopa monotherapy. We identified 116 patients on l-dopa monotherapy treated between 1965 and 1992 and followe
Autor:
Charity G. Moore, Melvin D. Yahr, Robert G. Holloway, Gregor K. Wenning, Cristina Sampaio, Glenn T. Stebbins, Carl Counsell, Nir Giladi, Werner Poewe, Olivier Rascol, Lisa Seidl, Christopher G. Goetz
Publikováno v:
Movement Disorders. 19:1020-1028
The Movement Disorder Society Task Force for Rating Scales for Parkinson's disease (PD) prepared a critique of the Hoehn and Yahr scale (HY). Strengths of the HY scale include its wide utilization and acceptance. Progressively higher stages correlate
Autor:
Melvin D. Yahr, David S. Goldstein, Daniela Saadia, Horacio Kaufmann, Andrei Voustianiouk, Courtney Holmes, Rachel Nardin, Roy Freeman
Publikováno v:
Circulation. 108:724-728
Background— In patients with neurogenic orthostatic hypotension (NOH), the availability of the sympathetic neurotransmitter norepinephrine (NE) in the synaptic cleft is insufficient to maintain blood pressure while in the standing posture. Methods
Publikováno v:
Parkinsonism & Related Disorders. 9:221-224
Less than a consensus exists as to whether chronic treatment with selegiline in combination with levodopa/carbidopa in patients with Parkinson's disease, is associated with more pronounced orthostatic hypotension than treatment with levodopa/carbidop
Publikováno v:
Parkinsonism & Related Disorders. 9:225-231
A multigenerational family complex with an admixture of essential tremor (ET) and PD is presented. Medical information obtained either by historic documentation and/or examination was available for five generations and included 36 members. Of these,
Autor:
Melvin D. Yahr
Publikováno v:
Parkinsonism & Related Disorders. 8:381-384
Autor:
A. Prikhojan, Peter Werner, Melvin D. Yahr, Susan B. Bressman, Teodoro Bottiglieri, Nicole Rempel, Alessandro Di Rocco
Publikováno v:
Brain Research. 893:278-281
l -dopa may be toxic to dopamine neurons, possibly due to catechol-autoxidation. Catechols are O -methylated by catechol- O -methyltransferase (COMT) in a SAM consuming reaction, preventing the initiation of catechol autoxidation. We hypothesized tha
Publikováno v:
Journal of Neural Transmission. 107:1159-1164
A paucity of studies are available concerning the comparative therapeutic effectiveness of presently available dopamine agonist agents in the control of Parkinson symptoms. To provide a basis for resolving this issue, we measured the circling respons
Autor:
Cheryl H. Waters, Abraham Lieberman, C. W. Olanow, Kapil D. Sethi, Phillip D. Swanson, Melvin D. Yahr, Howard I. Hurtig, Stanley Fahn
Publikováno v:
Neurology. 51:1057-1062
Objective: To evaluate the nonergot dopamine agonist ropinirole as an adjunct to L-dopa in a randomized, double-blind trial in PD patients with motor fluctuations.Background: L-dopa in the treatment of PD is associated with motor fluctuations, dyskin
Publikováno v:
Journal of Neural Transmission. 105:247-251
We report a patient with a parkinsonian syndrome induced by sertraline (Zoloft), an SSRI antidepressant, whose symptoms resolved after the drug was discontinued. This case prompted us to investigate the effect of sertraline on dopamine metabolism in