Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Melvin D. Reuber"'
Publikováno v:
Carcinogenesis. 1(2)
Nitrosomethyl-n-butylamine and its derivatives, labeled with deuterium in the methyl group or at the alpha position of the butyl group, were given to rats in drinking water at equimolar doses for approximately 20 weeks. Two concentrations were used,
Autor:
Warren, Bell, Richard, Clapp, Devra, Davis, Samuel, Epstein, Emmanuel, Farber, Donald A, Fox, Bruce, Holub, Michael F, Jacobson, William, Lijinsky, Erik, Millstone, Melvin D, Reuber, David, Suzuki, Norman J, Temple
Publikováno v:
International journal of occupational and environmental health. 8(4)
We appreciate this opportunity to provide input to the Health Protection Branch's (HPB's) review of the artificial sweetener saccharin. Concerns with regard to the safety of saccharin are of great public health significance and of great interest to t
Publikováno v:
International journal of occupational and environmental health. 8(3)
Autor:
Melvin D. Reuber
Publikováno v:
Digestion. 19:42-47
The maximal tolerated doses of dihydrosafrole, safrole, and isosafrole were given by continuous oral administration, starting at the age of 7 days, to both sexes of two hybrid strains of mice – (C57BL/6 X C3HAnf)F 1 and (C57BL/6 X AKR)F 1 . Hyperpl
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 106:171-175
The carcinogenic effectiveness of nitrosomethyl-n-butylamine,-n-hexylamine and -n-heptylamine was compared by administration to F344 rats at various concentrations in drinking water and by gavage in oil. Nitrosomethylbutylamine induced only tumors of
Autor:
William Lijinsky, Melvin D. Reuber
Publikováno v:
Cancer Letters. 16:273-279
Nitroso-N-methylurethane and nitroso-N-ethylurethane were administered to groups of 20 female F344 rats in corn oil solution by gavage. Each rat received once a week 0.2 ml of solution containing 7 mg/ml or 1.75 mg/ml of the methyl compound or 8 mg/m
Autor:
Melvin D. Reuber
Publikováno v:
The Bulletin of the Society of Pharmacological and Environmental Pathologists. 4:5-8
Autor:
Melvin D. Reuber
Publikováno v:
JNCI: Journal of the National Cancer Institute. 53:883-886
Publikováno v:
JNCI: Journal of the National Cancer Institute. 64:1537-1545
The histogenesis of renal adenocarcinoma induced in F344 rats by the carcinogen N-(4'-fluoro-4-biphenylyl)acetamide (FBPA) was described in order to clarify the site of origin of this neoplasm within the nephron. FBPA was added to the diet up to 48 w
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 107:178-182
Three asymmetric nitrosamines related to nitrosobis-(2-oxopropyl)-amine (BOP) were given to female F344 rats in drinking water to assess the significance of other alkyl groups on the carcinogenic expression by the 2-oxopropyl group. Nitroso-oxopropyl