Original COVID-19 priming regimen impacts the immunogenicity of bivalent BA.1 and BA.5 boosters

Autor: Luca M. Zaeck, Ngoc H. Tan, Wim J. R. Rietdijk, Daryl Geers, Roos S. G. Sablerolles, Susanne Bogers, Laura L. A. van Dijk, Lennert Gommers, Leanne P. M. van Leeuwen, Sharona Rugebregt, Abraham Goorhuis, Douwe F. Postma, Leo G. Visser, Virgil A. S. H. Dalm, Melvin Lafeber, Neeltje A. Kootstra, Anke L. W. Huckriede, Bart L. Haagmans, Debbie van Baarle, Marion P. G. Koopmans, SWITCH-ON Research Group, P. Hugo M. van der Kuy, Corine H. GeurtsvanKessel, Rory D. de Vries

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

Abstract Waning antibody responses after COVID-19 vaccination combined with the emergence of the SARS-CoV-2 Omicron lineage led to reduced vaccine effectiveness. As a countermeasure, bivalent mRNA-based booster vaccines encoding the ancestral spike p

Externí odkaz: https://doaj.org/article/7b4e0251847c419a88ac331e321a07cb

Analyzing the immunogenicity of bivalent booster vaccinations in healthcare workers: The SWITCH ON trial protocol

Autor: Ngoc H. Tan, Roos S. G. Sablerolles, Wim J. R. Rietdijk, Abraham Goorhuis, Douwe F. Postma, Leo G. Visser, Susanne Bogers, Daryl Geers, Luca M. Zaeck, Marion P. G. Koopmans, Virgil A. S. H. Dalm, Neeltje A. Kootstra, Anke L. W. Huckriede, Debbie van Baarle, Melvin Lafeber, Corine H. GeurtsvanKessel, Rory D. de Vries, Paul-Hugo Marie van der Kuy

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Vaccination against coronavirus disease 2019 (COVID-19) has contributed greatly to providing protection against severe disease, thereby reducing hospital admissions and deaths. Several studies have reported reduction in vaccine effectiveness over tim

Externí odkaz: https://doaj.org/article/1358e918a21143969773cb64ea909552

Association between Clinical Frailty Scale score and hospital mortality in adult patients with COVID-19 (COMET): an international, multicentre, retrospective, observational cohort study

Autor: Roos S G Sablerolles, MD, Melvin Lafeber, MD, Janneke A L van Kempen, MD, Bob P A van de Loo, Msc, Eric Boersma, ProfPhD, Wim J R Rietdijk, PhD, Harmke A Polinder-Bos, MD, Simon P Mooijaart, MD, Hugo van der Kuy, ProfPharmD, Jorie Versmissen, MD, Miriam C Faes, MD, LA Agnoletto, J Aleman, S Andreassi, LM Andrews, L Ashfield, H Bell, AKB Bengaard, SB Berlinghini, KB Bini, ZB Bisoffi, KB Blum, E Boemaars, GB Boni, TM Bosch, BE Bosma, F Boutkourt, C Bufarini, A Bulsink, RC Cabuk, GC Callens, MC Candela, MC Canonici, EC Capone, IC Carmo, FC Caruso, PC Chessa, GC Cohet, I Cornelissen-Wesseling, KML Crommentuijn, FM de Stoppelaar, HAJM de Wit, DS Deben, LJJ Derijks, MDC Di Carlo, J Diepstraten, B Dilek, DMK Duchek-Mann, MM Ebbens, LJ Ellerbroek, M Ezinga, MF Falcao, FF Falcao, LF Fantini, HF Farinha, PMG Filius, NJ Fitzhugh, G Fleming, TF Forsthuber, GG Gambarelli, MG Gambera, CGY García Yubero, Z Getrouw, CN Ghazarian, N Goodfellow, MQG Gorgas, RG Grinta, K Guda, DH Haider, J Hanley, KH Heitzeneder, WL Hemminga, LC Hendriksen, DL Hilarius, FEF Hogenhuis, IC Hoogendoorn-de Graaf, MBH Houlind, MAH Huebler, KPGM Hurkens, PKC Janssen, E Jong, MHW Kappers, KFM Keijzers, MK Kemogni, EM Kemper, RA Kranenburg, LL Krens, JL G Le Grand, J Liang, S Lim, NL Lindner, EL Loche, AL Lubich, B Maat, CM Maesano, AM Maiworm, M Maragna, FM Marchesini, IM Martignoni, G M Martini, CM Masini, R Mc Menamin, DM Mendes, M Miarons, R Moorlag, MR Müller, FN Nagele, KN Nemec, GO Oka, AG Otten-Helmers, SP Pagliarino, FP Pappalardo, M Patel, PM Peverini, FP Pieraccini, EMP Platania, NPK Pons-Kerjean, LPH Portillo Horcajada, GR Rametta, JR Rijo, EE Roelofsen, E Roobol-Meuwese, LR Rossi, SAH Russel, Z Safipour, FS Salaffi, L Saleh, AMS Schimizzi, JMGA Schols, MS Schwap, MG Scott, EAM Slijfer, EMA Slob, JS Soares, MS Solano, F Sombogaard, GS Stemer, MT Tardella, PGJ ter Horst, RT Tessari, J Tournoy, RB van den Berg, L Van der Linden, PD van der Linden, SC van Dijk, RW Van Etten, IMM van Haelst, M van Heuckelum, HJM van Kan, C van Nieuwkoop, HAW van Onzenoort, P van Wijngaarden, JDJ Verdonk, Fv Verri, JAMC Verstijnen, MV Veyrier, EV Viegas, LE Visser, A Vos, MAM Vromen, PC Wierenga, DR Wong, CZ Zenico, TZ Zuppini

Publikováno v: The Lancet. Healthy Longevity, Vol 2, Iss 3, Pp e163-e170 (2021)

Summary: Background: During the COVID-19 pandemic, the scarcity of resources has necessitated triage of critical care for patients with the disease. In patients aged 65 years and older, triage decisions are regularly based on degree of frailty measur

Externí odkaz: https://doaj.org/article/25542a489c0c438688fb4c4de1d44583

Association between renal sympathetic denervation and arterial stiffness: the ASORAS study

Autor: Victor J.M. Zeijen, Lida Feyz, Isabella Kardys, Marcel L. Geleijnse, Nicolas M. Van Mieghem, Felix Zijlstra, Melvin Lafeber, Rob J. Van Der Geest, Alexander Hirsch, Joost Daemen

Publikováno v: Journal of Hypertension, 41(3), 476-485. Lippincott Williams & Wilkins

OBJECTIVES: Renal sympathetic denervation (RDN) reduces blood pressure (BP). However, one out of three patients does not exhibit a significant BP response to the therapy. This study investigates the association between noninvasive vascular stiffness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7adbbf7f77cb1bf183f0ec4a89d23a3
https://pure.eur.nl/en/publications/14319563-83ae-4033-9035-85b6f17ed919

PS-C27-3: MEASURING ANTIHYPERTENSIVE DRUG CONCENTRATIONS TO DETERMINE NON-ADHERENCE IN HYPERTENSIVE PATIENTS WITH AND WITHOUT KIDNEY TRANSPLANTATION

Autor: Laura EJ Peeters, Dennis A Hesselink, Brenda CM de Winter, Melvin Lafeber, David Severs, Martijn WF van den Hoogen, Michelle AH Sonneveld, Chris RB Ramakers, Soma Bahmany, Teun van Gelder, Birgit CP Koch, Jorie Versmissen

Publikováno v: Journal of Hypertension. 41:e418

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcd77a83dec7470d1e814270890a863a
https://doi.org/10.1097/01.hjh.0000917120.31715.64