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Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies

Autor: Balakrishnan, K, Burton, T, Cannon, J, Collier, D, Coughlan, C, D'Souza, R, Enobakhare, E, Findlay, E, Gardiner-Hill, C, Gupta, P, Helmy, J, Helmy, C, Hobbs, L, Hobbs, R, Hood, S, Iles, R, Kean, S, Kwok, S, Lacy, P, MacIntyre, I, Mackay, J, Markandu, N, Martin, U, McCallum, L, McCann, G, McGinnis, A, Melville, V, Muir, S, Myint, KS, Nazir, S, Palmer, J, Papworth, R, Rutkowski, K, Saxena, M, Schumann, A, Soran, H, Stanley, A, Thom, S, Webb, A, White, C, Wilson, R, Zak, A, Williams, Bryan, MacDonald, Thomas M, Morant, Steve V, Webb, David J, Sever, Peter, McInnes, Gordon T, Ford, Ian, Cruickshank, J Kennedy, Caulfield, Mark J, Padmanabhan, Sandosh, Mackenzie, Isla S, Salsbury, Jackie, Brown, Morris J

Publikováno v: In The Lancet Diabetes & Endocrinology June 2018 6(6):464-475

Effects of Spironolactone and Chlorthalidone on Cardiovascular Structure and Function in Chronic Kidney Disease: A Randomized, Open-Label Trial.

Autor: Edwards NC; Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom.; Department of Cardiology, Green Lane Cardiovascular Unit, Auckland, New Zealand., Price AM; Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom.; Department of Nephrology, Queen Elizabeth Hospital, Birmingham, United Kingdom., Mehta S; Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom., Hiemstra TF; Cambridge Clinical Trials Unit, Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, United Kingdom.; GlaxoSmithKline, England, United Kingdom., Kaur A; Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom., Greasley PJ; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Webb DJ; Center for Cardiovascular Science and Clinical Research Center, University of Edinburgh, United Kingdom., Dhaun N; Center for Cardiovascular Science and Clinical Research Center, University of Edinburgh, United Kingdom.; Department of Nephrology, National Health Services Lothian, Edinburgh, United Kingdom., MacIntyre IM; Center for Cardiovascular Science and Clinical Research Center, University of Edinburgh, United Kingdom.; Department of Nephrology, National Health Services Lothian, Edinburgh, United Kingdom., Farrah T; Center for Cardiovascular Science and Clinical Research Center, University of Edinburgh, United Kingdom.; Department of Nephrology, National Health Services Lothian, Edinburgh, United Kingdom., Melville V; Center for Cardiovascular Science and Clinical Research Center, University of Edinburgh, United Kingdom., Herrey AS; UCL Institute of Cardiovascular Science and Department of Cardiology, Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom., Slinn G; Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom., Wale R; Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom., Ives N; Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom., Wheeler DC; Department of Renal Medicine, University College London, United Kingdom.; George Institute for Global Health, Sydney, Australia., Wilkinson I; Cambridge Clinical Trials Unit, Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, United Kingdom.; GlaxoSmithKline, England, United Kingdom., Steeds RP; Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom.; Department of Cardiology, Queen Elizabeth Hospital Birmingham, United Kingdom., Ferro CJ; Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom.; Department of Nephrology, Queen Elizabeth Hospital, Birmingham, United Kingdom., Townend JN; Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom.; Department of Cardiology, Queen Elizabeth Hospital Birmingham, United Kingdom.

Publikováno v: Clinical journal of the American Society of Nephrology : CJASN [Clin J Am Soc Nephrol] 2021 Oct; Vol. 16 (10), pp. 1491-1501. Date of Electronic Publication: 2021 Aug 30.

Combination therapy is superior to sequential monotherapy for the initial treatment of hypertension: A double-blind randomized controlled trial

Autor: MacDonald, TM, Williams, B, Webb, DJ, Morant, S, Caulfield, M, Cruickshank, JK, Ford, I, Sever, P, Mackenzie, IS, Padmanabhan, S, McCann, GP, Salsbury, J, McInnes, G, Brown, MJ, Schumann, A, Helmy, J, Maniero, C, Burton, TJ, Quinn, U, Hobbs, L, Palmer, J, Collier, D, Markandu, N, Saxena, M, Zak, A, Enobakhare, E, Mackay, J, Thom, SA, Coughlan, C, McGinnis, AR, Findlay, E, Stanley, AG, White, C, Lacy, P, Gardiner-Hill, CJ, Nazir, S, McInnes, GT, Muir, S, McCallum, L, Melville, V, MacIntyre, IM, Brown, R, Simon, R, Soran, H, Kwok, S, Balakrishnan, K, Hobbs, R, Iles, R, Myint, KS, Cannon, J, Hood, S, Rutkowski, K, Webb, A, Martin, U, Kean, S, Wilson, R, Papworth, R

Publikováno v: Journal of the American Heart Association. 6(11)

Background--Guidelines for hypertension vary in their preference for initial combination therapy or initial monotherapy, stratified by patient profile; therefore, we compared the efficacy and tolerability of these approaches. Methods and Results--We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8c72d380f66b1c05efd1a51ef799ea79
http://ora.ox.ac.uk/objects/uuid:

Association between Visit-to-Visit Ultrafiltration Volume Variability, Vascular Biomarkers and Cardiovascular Parameters in Chronic Hemodialysis Patients.

Autor: Sági, Balázs^1,2 (AUTHOR) balazs.sagidr28@gmail.com, Vas, Tibor¹ (AUTHOR) vas.tibor@pte.hu, Jakabfi-Csepregi, Rita Klaudia^3,4 (AUTHOR) ritacsepregi93@gmail.com, Sulyok, Endre⁵ (AUTHOR) esulyok@t-online.hu, Csiky, Botond^1,2 (AUTHOR) botond.csiky@gmail.com

Publikováno v: Journal of Clinical Medicine. Oct2024, Vol. 13 Issue 19, p5958. 11p.