Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Meltz Clifford Nathaniel"'
Autor:
Michel Couturier, Paul Bowles, Morgan Meltz, Robert A. Singer, Gregory Lee Karrick, Lulin Wei, Meltz Clifford Nathaniel, John A. Ragan, Ruth E. McDermott, Dennis E. Bourassa, James E. Phillips, Michael J. Castaldi, Ronald J. Clay, Justin Beaudin, John L. Tucker, Teresa W. Makowski, David H. Brown Ripin
Publikováno v:
Organic Process Research & Development. 7:873-878
The synthesis of 6-ethoxy-4-oxo-1,4-dihydro-[1,5]naphthyridine-3-carboxylic acid benzylamide (1) on multikilogram scale is described. The major challenge for the synthesis of this quinolone GABA partial agonist was in the isolation of product of acce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15ad0142e3b287ae0fdbef95483ccc4e
https://doi.org/10.1021/op0341061
https://doi.org/10.1021/op0341061
Publikováno v:
Synthesis. 2002:483-486
A practical synthesis of 4-hydroxymethyl-2-methylpyridine has been developed which makes use of Evans' regioselective lithiation of readily available 2,4-lutidine and trapping with dimethylformamide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b8d99cb298064eabbe6ae01512cf324
https://doi.org/10.1055/s-2002-20960
https://doi.org/10.1055/s-2002-20960
Publikováno v:
Tetrahedron Letters. 24:4507-4510
Thiazolidines generated by the addition of ketone enolates to boron trifluoride activated 2,2,5-trialkyl-3-thiazolines undergo a facile acid catalyzed conversion to di- and trisubstituted thiophenes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::015ed4fb8848c4c395ef1df0770ff233
https://doi.org/10.1016/s0040-4039(00)85940-7
https://doi.org/10.1016/s0040-4039(00)85940-7
Publikováno v:
Tetrahedron Letters. 24:4503-4506
Boron trifluoride activated 2,2,5-trialkyl-3-thiazolines react with a wide range of organometallic reagents to generate substituted thiazolidines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a0fc9bc571a477687c760e40ab15982
https://doi.org/10.1016/s0040-4039(00)85939-0
https://doi.org/10.1016/s0040-4039(00)85939-0