Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Melony S. O'Neill"'
Autor:
Melony S. O’Neill, Bryan Husbeck, Shoucheng Ning, Marianne Broome Powell, Susan J. Knox, Mark Hsu, Zhijian Chen, Amie J. Dirks, Barbara Bedogni
Publikováno v:
Radiation Research. 168:125-133
The integrins and PI3K/Akt are important mediators of the signal transduction pathways involved in tumor angiogenesis and cell survival after exposure to ionizing radiation. Selective targeting of either integrins or PI3K/Akt can radiosensitize tumor
Autor:
Amato J. Giaccia, Scott M. Welford, Melony S. O’Neill, Nicholas C. Denko, Marianne Broome Powell, Barbara Bedogni, Donna M. Bouley
Publikováno v:
Cancer research. 64(7)
Topical treatment with inhibitors of the phosphatidylinositol 3′-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways inhibited the growth of TPras transgenic melanomas in severe combined immunod