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Peptide transport by the multidrug resistance protein MRP1

Autor: de Jong, M. C., Slootstra, J. W., Scheffer, G. L., Schroeijers, A. B., Puijk, W. C., Dinkelberg, R., Kool, M., Broxterman, H. J., Meloen, R. H., Scheper, R. J.

Publikováno v: Cancer research, 61(6), 2552-2557. American Association for Cancer Research Inc.

Small hydrophobic peptides were studied as possible substrates of the multidrug resistance protein (MRP)-1 (ABCC1) transmembrane transporter molecule. As observed earlier for P-glycoprotein- (Pgp; ABCB1) overexpressing cells, MRP1-overexpressing cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::1e3ae811b889aabc294f8ab9894490ca
https://pure.amc.nl/en/publications/peptide-transport-by-the-multidrug-resistance-protein-mrp1(870e63a6-a123-41f5-8651-e2b1605fbc11).html

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Edible vaccines

Autor: Meloen, R. H., Hamilton, W. D. O., J. Ignacio Casal, Dalsgaard, K., Langeveld, J. P. M.

Publikováno v: Veterinary Quarterly, 20(SUPPL. 3), S92-S95
Veterinary Quarterly 20 (1998) SUPPL. 3
Scopus-Elsevier

The ultimate vaccine is an oral vaccine which given once protects against a multitude of diseases. Furthermore this ultimate vaccine needs to be very stable and inexpensive to produce. Probably this latter condition can be met only if the vaccines ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2500986f52853b16ad6942cac3c79c2
https://research.wur.nl/en/publications/edible-vaccines

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T cell-stimulatory fragments of foot-and-mouth disease virus released by mild treatment with cathepsin D

Autor: Van Lierop, M. J.C., Van Noort, J. M., Wagenaar, J. P.A., Rutten, V. P.M.G., Langeveld, J., Meloen, R. H., Hensen, E. J., Leerstoel Baar, Immunologie, dI&I RA-I&I I&I, Geochemistry, Utrecht Life Sciences

Publikováno v: Journal of General Virology, 75(11), 2937. Society for General Microbiology
Scopus-Elsevier

Cathepsin D and cathepsin B are endosomal/lysosomal proteases that are thought to play a role during in vivo antigen processing, releasing fragments for binding to major histocompatibility complex class II products and subsequent presentation to T ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a054f8c12a65bf09647bf3cc377621dd
https://dspace.library.uu.nl/handle/1874/412104

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Proliferative lymphocyte responses to foot-and-mouth disease virus and three FMDV peptides after vaccination or immunization with these peptides in cattle

Autor: van Lierop, M J, van Maanen, K, Meloen, R H, Rutten, V P, de Jong, M A, Hensen, E J

We studied proliferative responses of bovine T lymphocytes to foot-and-mouth disease virus (FMDV) serotypes A, O and C as well as to three peptides including the two major B-cell epitopes of FMDV (VP1[141-156] and VP1[200-213]). Peripheral blood mono

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e09f615cce1a92fcf2f2f09104649932
https://europepmc.org/articles/PMC1384732/

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Linear neutralizing epitopes on the peplomer protein of coronaviruses

Autor: Posthumus, W. P A, Meloen, R. H., Enjuanes, L., Correa, I., van Nieuwstadt, A. P., Koch, G., de Groot, R. J., Kusters, J. G., Luytjes, W., Spaan, W. J., van der Zeijst, B. A M, Lenstra, J. A.

Three years ago, we reported a comparison of the primary structures of the S peplomer proteins of three coronaviruses - mouse hepatitis virus (MHV, strain A59), infectious bronchitis virus (IBV, strain M41), and feline infectious peritonitis virus (F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::d1ebe3227d8af015a9d88e336af4ae85
https://dspace.library.uu.nl/handle/1874/394995

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Location of antigenic sites of the S-glycoprotein of transmissible gastroenteritis virus and their conservation in coronaviruses

Autor: Enjuanes, L., Gebauer, F., Correa, I., Bullido, M. J., Sune, C., Smerdou, C., Sanchez, C., Lenstra, J. A., Posthumus, W. P A, Meloen, R. H., LS IRAS Tox Algemeen, Sub ULS

Publikováno v: Coronaviruses and their Diseases, 276, 159. Springer
Advances in Experimental Medicine and Biology ISBN: 9781468458251

Transmissible gastroenteritis virus (TGEV) has a single-stranded, positive-sense RNA genome of more than 20 kb (Brian et al., 1980; Rasschaert et al., 1987) and three structural proteins: S, N and M, with 1447, 382 and 262 amino acids, respectively (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a2d7591c371e286d8ddd2318f8aaca
https://dspace.library.uu.nl/handle/1874/394996

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