Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Melody L. Woods"'
Autor:
Melody L. Woods, Renee M. Hein
Publikováno v:
Immunology Letters. 108:103-108
T-cell immunoglobulin mucin-1 (TIM-1) is associated with the regulation of T helper type 2 (Th2) immune responses and has been associated with asthma susceptibility. Previous studies have shown that administration of TIM-1 results in T cell hyperprol
Signaling networks regulating β1 integrin-mediated adhesion of T lymphocytes to extracellular matrix
Autor:
Melody L. Woods, Yoji Shimizu
Publikováno v:
Journal of Leukocyte Biology. 69:874-880
T-cell recognition of foreign antigen and migration to specific anatomic sites in vivo involves transient adhesive contacts between b1 integrins expressed on T cells and cell surface pro- teins or extracellular-matrix components. Engage- ment of the
Publikováno v:
European Journal of Immunology. 30:38-49
The relationship between activation-dependent changes in beta1 integrin conformation, T cell adhesion to immobilized fibronectin, and T cell migration in vitro was analyzed in this study. Stimulation of Jurkat T cells and peripheral T cells with Mn(2
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 34:93-101
Purpose : The purpose of this work was to evaluate EF5, a 2-nitroimidazole compound, and anti-EF5 antibodies as a method to quantify radiobologically hypoxic cells. Methods and Materials : Multicellular spheroids of EMT6 mammary sarcoma cells were us
Autor:
Melody L. Woods, Beth A. Pulaski, Edith M. Lord, John G. Frelinger, Alexander J. McAdam, Anthony A. Gaspari, Kun Yun Yeh
Publikováno v:
Cellular Immunology. 165:217-224
The B7-1 molecule expressed on antigen presenting cells is an important costimulatory molecule for T cell activation. It has been demonstrated that murine B7-1 can enhance host immunity and lead to tumor rejection via its costimulatory function. Here
Publikováno v:
European journal of immunology. 35(12)
The B7 family member programmed death ligand 2 (PD-L2) has been implicated in both positive and negative regulation of T cell activity. In this study, we demonstrate that on human T cells, PD-L2 acts only as a negative regulator of T cell activity, i
Publikováno v:
Scopus-Elsevier
One of the earliest functional responses of T lymphocytes to extracellular signals that activate the Ag-specific CD3/TCR complex is a rapid, but reversible, increase in the functional activity of integrin adhesion receptors. Previous studies have imp
Autor:
Peggy Myung, Jennifer N. Wu, Gary A. Koretzky, Yoji Shimizu, Qing-Hua Liu, Sally A. Dmowski, Jonathan T. Pribila, Martha S. Jordan, Bruce D. Freedman, Geo Derimanov, Melody L. Woods, Erik J. Peterson
Publikováno v:
Science (New York, N.Y.). 293(5538)
SLAP-130/Fyb (SLP-76–associated phosphoprotein or Fyn-binding protein; also known as Fyb/Slap) is a hematopoietic-specific adapter, which associates with and modulates function of SH2-containing leukocyte phosphoprotein of 76 kilodaltons (SLP-76).
Publikováno v:
The EMBO journal. 20(6)
Stimulation of T cells via the CD3--T-cell receptor (TCR) complex results in rapid increases in beta 1 integrin-mediated adhesion via poorly defined intracellular signaling events. We demonstrate that TCR-mediated activation of beta 1 integrins requi
Autor:
A. Felcher, Elizabeth K. Hutter, Beth A. Pulaski, John G. Frelinger, Melody L. Woods, Edith M. Lord, Alexander J. McAdam
Publikováno v:
Annals of the New York Academy of Sciences. 690