Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Melody L. Mak-Jurkauskas"'
Autor:
Andrew M. Clausen, Karl B. Hansen, L. Steven Hollis, Melody L. Mak-Jurkauskas, Matthew M. Bio, Steven M. Mennen, Kelly A. Nadeau
Publikováno v:
Organic Process Research & Development. 19:884-891
A simple one-pot, two-step process for the conversion of 2-acylbenzoic acids to phthalazin-1(2H)-ones was developed. A robust process was required that delivered the final isolated solid with consistently low levels of residual hydrazine, for further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::112ee808aa962011e1fa59c061d82a56
https://doi.org/10.1021/acs.oprd.5b00135
https://doi.org/10.1021/acs.oprd.5b00135
Autor:
Vladimir K. Michaelis, Ta-Chung Ong, Melody L. Mak-Jurkauskas, Albert A. Smith, Timothy M. Swager, Björn Corzilius, Robert G. Griffin, Andrew M. Clausen, Joseph J. Walish, Janet Cheetham
Publikováno v:
The Journal of Physical Chemistry B. 117:3040-3046
Dynamic nuclear polarization (DNP) of amorphous and crystalline ortho-terphenyl (OTP) in the absence of glass forming agents is presented in order to gauge the feasibility of applying DNP to pharmaceutical solid-state nuclear magnetic resonance exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b418ffa38b9fed6ff9aad0cd83d39b51
https://doi.org/10.1021/jp311237d
https://doi.org/10.1021/jp311237d
Autor:
Eugenio Daviso, Judith Herzfeld, Irena Mamajanov, Danielle Rand, Melody L. Mak-Jurkauskas, Yoh Matsuki
Publikováno v:
The Journal of Physical Chemistry B. 115:5741-5745
Sugar-derived humins and melanoidins figure significantly in food chemistry, agricultural chemistry, biochemistry, and prebiotic chemistry. Despite wide interest and significant experimental attention, the amorphous and insoluble nature of the polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd548aacb4b965e6cc55adea018e9d6
https://doi.org/10.1021/jp1119662
https://doi.org/10.1021/jp1119662
Autor:
Vikram S. Bajaj, Judith Herzfeld, M.K. Hornstein, Robert G. Griffin, Melody L. Mak-Jurkauskas, Marina Belenky
Publikováno v:
Proceedings of the National Academy of Sciences. 105:883-888
By exploiting dynamic nuclear polarization (DNP) at 90 K, we observe the first NMR spectrum of the K intermediate in the ion-motive photocycle of bacteriorhodopsin. The intermediate is identified by its reversion to the resting state of the protein i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b81601ab9e44c7a1a60687b0548dfd
https://doi.org/10.1073/pnas.0706156105
https://doi.org/10.1073/pnas.0706156105
Autor:
L. Steven Hollis, Melody L. Mak-Jurkauskas, Matthew M. Bio, Karl B. Hansen, Kelly A. Nadeau, Andrew M. Clausen, Steven M. Mennen
Publikováno v:
ChemInform. 46
A simple one-pot, two-step process for the conversion of 2-acylbenzoic acids to phthalazin-1(2H)-ones was developed. A robust process was required that delivered the final isolated solid with consistently low levels of residual hydrazine, for further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5564cbf6b76b6da000409f6d8db47f8a
https://doi.org/10.1002/chin.201547178
https://doi.org/10.1002/chin.201547178
Publikováno v:
Journal of laboratory automation. 18(1)
The release profile of active pharmaceutical ingredient (API) from its solid dosage form is an important aspect of drug development as it is often used to predict potential drug release characteristics of a product in vivo. In recent years, magnetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9315a5308f88ad45187c039911daced
https://pubmed.ncbi.nlm.nih.gov/22933617
https://pubmed.ncbi.nlm.nih.gov/22933617
Nuclear magnetic resonance (NMR) provides unparalleled information on molecular structure and intermolecular interactions with atomic-level resolution, but it nevertheless lacks sensitivity in comparison to other forms of spectroscopy. This problem i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7efaf06b850ca81836a9200f2aed99d3
https://doi.org/10.1002/9780470034590.emrstm1183
https://doi.org/10.1002/9780470034590.emrstm1183
Autor:
Robert G. Griffin, Marina Belenky, Vikram S. Bajaj, Melody L. Mak-Jurkauskas, Judith Herzfeld
Publikováno v:
PMC
We describe a new approach to multiple [superscript 13]C–[superscript 15]N distance measurements in uniformly labeled solids, frequency-selective (FS) TEDOR. The method shares features with FS-REDOR and ZF- and BASE-TEDOR, which also provide quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c81a7c5b74f1ce5726c2c1ab6c92193
http://hdl.handle.net/1721.1/71967
http://hdl.handle.net/1721.1/71967
Autor:
Robert G. Griffin, Melody L. Mak-Jurkauskas, Marina Belenky, Vikram S. Bajaj, Judith Herzfeld
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(23)
Observation and structural studies of reaction intermediates of proteins are challenging because of the mixtures of states usually present at low concentrations. Here, we use a 250 GHz gyrotron (cyclotron resonance maser) and cryogenic temperatures t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19586cd741fa42cbe089bab39b40be88
https://pubmed.ncbi.nlm.nih.gov/19474298
https://pubmed.ncbi.nlm.nih.gov/19474298
Autor:
Melody L. Mak-Jurkauskas, Vikram S. Bajaj, Judith Herzfeld, Marina Belenky, Robert G. Griffin
Publikováno v:
Biophysical Journal. 96(3)
Bacteriorhodopsin (bR) is a 26 kDa archaeal membrane protein that harvests light energy to create an ion gradient across the cell membrane. Photoisomierzation of the retinilydene chromophore is coupled to ion translocation via a sequence of photocycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921b25f7245631f7102631c1d8efc429