Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Melody Baddoo"'
Autor:
Justin W. Magrath, Dane A. Flinchum, Alifiani B. Hartono, Shruthi Sanjitha Sampath, Tina M. O’Grady, Melody Baddoo, Liang Haoyang, Xiaojiang Xu, Erik K. Flemington, Sean B. Lee
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-15 (2024)
Abstract Desmoplastic small round cell tumor (DSRCT) is an aggressive pediatric cancer caused by the EWSR1-WT1 fusion oncoprotein. The tumor is refractory to treatment with a 5-year survival rate of only 15–25%, necessitating the development of nov
Externí odkaz:
https://doaj.org/article/a8a2471577974e2b8bcfdaa509733192
Autor:
Mona Elgazzaz, Clara Berdasco, Jone Garai, Melody Baddoo, Shiping Lu, Hisham Daoud, Jovanny Zabaleta, Franck Mauvais-Jarvis, Eric Lazartigues
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101864- (2024)
Objective: Maternal exposure during pregnancy is a strong determinant of offspring health outcomes. Such exposure induces changes in the offspring epigenome resulting in gene expression and functional changes. In this study, we investigated the effec
Externí odkaz:
https://doaj.org/article/6489b879ed3342e9a6f9cdf90331e953
SCIFER: approach for analysis of LINE-1 mRNA expression in single cells at a single locus resolution
Autor:
Emily C. Stow, Melody Baddoo, Alexis J. LaRosa, Dawn LaCoste, Prescott Deininger, Victoria Belancio
Publikováno v:
Mobile DNA, Vol 13, Iss 1, Pp 1-20 (2022)
Abstract Background Endogenous expression of L1 mRNA is the first step in an L1-initiated mutagenesis event. However, the contribution of individual cell types to patterns of organ-specific L1 mRNA expression remains poorly understood, especially at
Externí odkaz:
https://doaj.org/article/eb7e2933ba034fd3a88cf17d82998512
Autor:
Tina M. O’Grady, Melody Baddoo, Samuel A. Flemington, Eman Y. Ishaq, Nathan A. Ungerleider, Erik K. Flemington
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionB cell activation and differentiation is central to the adaptive immune response. Changes in exon usage can have major impacts on cellular signaling and differentiation but have not been systematically explored in differentiating B cells.
Externí odkaz:
https://doaj.org/article/9ddc30d1071c41caa874aa80b3fa81b5
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Joshua S. Samudre, Morgan E. Collins, Alifiani B. Hartono, Sean B. Lee, Frank Lau, Melody Baddoo, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)
Abstract Obesity is a worldwide epidemic associated with increased risk and progression of colon cancer. Here, we aimed to determine the role of adipose triglyceride lipase (ATGL), responsible for intracellular lipid droplet (LD) utilization, in obes
Externí odkaz:
https://doaj.org/article/dad0fa3c4c914a0ebba7e45d5f2c7f93
Autor:
Emmanuelle Ruiz, Harrison M. Penrose, Sandra Heller, Hani Nakhoul, Melody Baddoo, Erik F. Flemington, Emad Kandil, Suzana D. Savkovic
Publikováno v:
Gut Microbes, Vol 11, Iss 3, Pp 350-363 (2020)
Inflammatory bowel disease (IBD) has been linked to active signaling with bacterial components and reduced mitochondrial ATP production; however, synergism between both of these disease characteristics remains unclear. We aimed to determine in human
Externí odkaz:
https://doaj.org/article/15355e26874241f1bf6b0de62ccbd1f3
Autor:
Harrison M. Penrose, Chloe Cable, Sandra Heller, Nathan Ungerleider, Hani Nakhoul, Melody Baddoo, Alifiani B. Hartono, Sean B. Lee, Matthew E. Burow, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 391-408 (2019)
Background & Aims: Diminished forkhead box O3 (FOXO3) function drives inflammation and cancer growth; however, mechanisms fostering these pathobiologies are unclear. Here, we aimed to identify in colon loss of FOXO3-dependent cellular and molecular c
Externí odkaz:
https://doaj.org/article/7337e8aa807f4d11a94daa9ce23793f7
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Joshua S. Samudre, Morgan E. Collins, Alifiani B. Hartono, Sean B. Lee, Frank Lau, Melody Baddoo, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/df3e440f84514614aa5dd372b8cc26ab
Autor:
Ma. Del Rocio Baños-Lara, Jovanny Zabaleta, Jone Garai, Melody Baddoo, Antonieta Guerrero-Plata
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-7 (2018)
Abstract Objective Human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) are responsible for respiratory diseases, mostly in children. Despite the clinical and epidemiological similarities between these two pneumoviruses, they elicit dif
Externí odkaz:
https://doaj.org/article/1b6cb9b86c6d4959aac3a5116b6f68f8
Autor:
Sylvia Hilliard, Renfang Song, Hongbing Liu, Chao-hui Chen, Yuwen Li, Melody Baddoo, Erik Flemington, Alanna Wanek, Jay Kolls, Zubaida Saifudeen, Samir S. El-Dahr
Publikováno v:
Biology Open, Vol 8, Iss 5 (2019)
Six2+ cap mesenchyme cells, also called nephron progenitor cells (NPC), are precursors of all epithelial cell types of the nephron, the filtering unit of the kidney. Current evidence indicates that perinatal ‘old’ NPC have a greater tendency to e
Externí odkaz:
https://doaj.org/article/0cd0ec4a59ae40ed910bd19e03746fd7