Zobrazeno 1 - 10
of 894
pro vyhledávání: '"Melody A, Swartz"'
Autor:
Lisa R. Volpatti, Rachel P. Wallace, Shijie Cao, Michal M. Raczy, Ruyi Wang, Laura T. Gray, Aaron T. Alpar, Priscilla S. Briquez, Nikolaos Mitrousis, Tiffany M. Marchell, Maria Stella Sasso, Mindy Nguyen, Aslan Mansurov, Erica Budina, Ani Solanki, Elyse A. Watkins, Mathew R. Schnorenberg, Andrew C. Tremain, Joseph W. Reda, Vlad Nicolaescu, Kevin Furlong, Steve Dvorkin, Shann S. Yu, Balaji Manicassamy, James L. LaBelle, Matthew V. Tirrell, Glenn Randall, Marcin Kwissa, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
Externí odkaz:
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Lymphatic endothelial cells prime naïve CD8+ T cells into memory cells under steady-state conditions
Autor:
Efthymia Vokali, Shann S. Yu, Sachiko Hirosue, Marcela Rinçon-Restrepo, Fernanda V. Duraes, Stefanie Scherer, Patricia Corthésy-Henrioud, Witold W. Kilarski, Anna Mondino, Dietmar Zehn, Stéphanie Hugues, Melody A. Swartz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Lymphatic endothelial cells (LECs) can cross-present antigen to naïve CD8+ T cells, but the significance of this interaction was unclear. Here the authors show that LECs directly induce CD8+ T cell differentiation with memory-like phenotypes, migrat
Externí odkaz:
https://doaj.org/article/f23b98b899c044b5baa15c4c746b6da2
Autor:
Chitavi D. Maulloo, Shijie Cao, Elyse A. Watkins, Michal M. Raczy, Ani. S. Solanki, Mindy Nguyen, Joseph W. Reda, Ha-Na Shim, D. Scott Wilson, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Inverse vaccines that tolerogenically target antigens to antigen-presenting cells (APCs) offer promise in prevention of immunity to allergens and protein drugs and treatment of autoimmunity. We have previously shown that targeting hepatic APCs throug
Externí odkaz:
https://doaj.org/article/99a335f0b63f44b78429ca41ed9d3d85
Autor:
Witold W. Kilarski, Coralie Martin, Marco Pisano, Odile Bain, Simon A Babayan, Melody A. Swartz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Stimuli affecting migration of filaria in host tissues are unclear. Using in situ imaging, Kilarski et al. here show that universal adaptations of nematodes allow Litomosoides sigmodontis infective larvae to mechanically break into pre-collecting lym
Externí odkaz:
https://doaj.org/article/2895c74fae134b2faea9fd113159dbc2
Autor:
Alexandra I. Magold, Melody A. Swartz
Publikováno v:
Cells, Vol 11, Iss 6, p 979 (2022)
Lymphatic vessels provide a critical line of communication between peripheral tissues and their draining lymph nodes, which is necessary for robust immune responses against infectious agents. At the same time, lymphatics help shape the nature and kin
Externí odkaz:
https://doaj.org/article/44d2325754604f33b5f2d193bca94fdc
Autor:
Priscilla S. Briquez, Sylvie Hauert, Alexandre de Titta, Laura T. Gray, Aaron T. Alpar, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Therapeutic cancer vaccines constitute a valuable tool to educate the immune system to fight tumors and prevent cancer relapse. Nevertheless, the number of cancer vaccines in the clinic remains very limited to date, highlighting the need for further
Externí odkaz:
https://doaj.org/article/9eca26893cb745aa9eca7fe5280c4192
Autor:
Natalia K. Botelho, Benjamin O. Tschumi, Jeffrey A. Hubbell, Melody A. Swartz, Alena Donda, Pedro Romero
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cross-presenting Xcr1+CD8α DCs are attractive APCs to target for therapeutic cancer vaccines, as they are able to take up and process antigen from dying tumor cells for their MHCI-restricted presentation to CD8 T cells. To this aim, we developed fus
Externí odkaz:
https://doaj.org/article/53366c80ef3841c8b314ac8bc79e804a
Autor:
Douglas Hanahan, Melody A. Swartz, Lisa M. Coussens, Alan J. Korman, Wesley Horton, Nadine Zangger, Dhaarini Murugan, Mélanie Tichet, Stephan Wullschleger, Gabriele Galliverti
Cancers induced by human papillomaviruses (HPV) should be responsive to immunotherapy by virtue of expressing the immunogenic oncoproteins E6/E7. However, advanced forms of cervical cancer, driven by HPV, are poorly responsive to immune response–en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1820704b78feea6b9c16767badac9930
https://doi.org/10.1158/2326-6066.c.6550152.v1
https://doi.org/10.1158/2326-6066.c.6550152.v1
Autor:
Stéphanie Hugues, Melody A. Swartz, Christoph Scheiermann, Robert Pick, Ludovic J. Wrobel, Dale Brighouse, Guillaume Harlé, Julien Angelillo, Juan Dubrot, Laure Garnier, Anastasia O. Gkountidi
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97b74bf408b56577d84cd79640dae10
https://doi.org/10.1158/2326-6066.22543177.v1
https://doi.org/10.1158/2326-6066.22543177.v1
Autor:
Stéphanie Hugues, Melody A. Swartz, Christoph Scheiermann, Robert Pick, Ludovic J. Wrobel, Dale Brighouse, Guillaume Harlé, Julien Angelillo, Juan Dubrot, Laure Garnier, Anastasia O. Gkountidi
Several solid malignancies trigger lymphangiogenesis, facilitating metastasis. Tumor-associated lymphatic vessels significantly contribute to the generation of an immunosuppressive tumor microenvironment (TME). Here, we have investigated the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2363ce973488adde34a9b575d30608b9
https://doi.org/10.1158/2326-6066.c.6550168.v1
https://doi.org/10.1158/2326-6066.c.6550168.v1