Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Melody, Cheong"'
Autor:
Kate H. Gartlan, Antiopi Varelias, Motoko Koyama, Renee J. Robb, Kate A. Markey, Karshing Chang, Andrew N. Wilkinson, David Smith, Md Ashik Ullah, Rachel D. Kuns, Neil C. Raffelt, Stuart D. Olver, Katie E. Lineburg, Bianca E. Teal, Melody Cheong, Michele W.L. Teng, Mark J. Smyth, Siok-Keen Tey, Kelli P.A. MacDonald, Geoffrey R. Hill
Publikováno v:
Blood Advances, Vol 1, Iss 6, Pp 341-351 (2017)
Abstract: T-helper 17 (Th17) cells have been widely implicated as drivers of autoimmune disease. In particular, Th17 cytokine plasticity and acquisition of an interleukin-17A+(IL-17A+)interferon γ(IFNγ)+ cytokine profile is associated with increase
Externí odkaz:
https://doaj.org/article/df05b8e5031c4704855ef42d306ae5c3
Autor:
Geoffrey R. Hill, Motoko Koyama, Mariapia A. Degli-Esposti, Joseph A. Trapani, Kelli P.A. MacDonald, Christian R. Engwerda, Mark J. Smyth, Glen M. Boyle, Kate A. Markey, Slavica Vuckovic, Antiopi Varelias, Greg Kelly, Vivien R. Sutton, Karshing Chang, Jose Paulo Martins, Christopher E. Andoniou, Rachel D. Kuns, Ping Zhang, Siok-Keen Tey, Jason S. Lee, Kate H. Gartlan, Melody Cheong
Supplementary Table S1 (related to Fig. 4A): (A) Ingenuity Pathway Analysis derived from the uncorrected dataset displaying top canonical signaling pathways involving differentially regulated genes in recipients as described in Fig.4A. (B) 10 selecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b81f04af8f07416c8522368ebdbf6e4
https://doi.org/10.1158/2326-6066.22543105.v1
https://doi.org/10.1158/2326-6066.22543105.v1
Autor:
Geoffrey R. Hill, Motoko Koyama, Mariapia A. Degli-Esposti, Joseph A. Trapani, Kelli P.A. MacDonald, Christian R. Engwerda, Mark J. Smyth, Glen M. Boyle, Kate A. Markey, Slavica Vuckovic, Antiopi Varelias, Greg Kelly, Vivien R. Sutton, Karshing Chang, Jose Paulo Martins, Christopher E. Andoniou, Rachel D. Kuns, Ping Zhang, Siok-Keen Tey, Jason S. Lee, Kate H. Gartlan, Melody Cheong
Supplementary Figure S1: GVHD survival of lethally-irradiated (day 0, 1000cGy split dose) B6.WT, B6.ASC-/- or B6.NLRP3-/- recipients transplanted with BALB/c BM (5x106) and T cells (5x106). The non-GVHD control group received TCD BM cells (5x106) onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c670406bdd6e90ec2d85cea9452ca1
https://doi.org/10.1158/2326-6066.22543108
https://doi.org/10.1158/2326-6066.22543108
Autor:
Geoffrey R. Hill, Motoko Koyama, Mariapia A. Degli-Esposti, Joseph A. Trapani, Kelli P.A. MacDonald, Christian R. Engwerda, Mark J. Smyth, Glen M. Boyle, Kate A. Markey, Slavica Vuckovic, Antiopi Varelias, Greg Kelly, Vivien R. Sutton, Karshing Chang, Jose Paulo Martins, Christopher E. Andoniou, Rachel D. Kuns, Ping Zhang, Siok-Keen Tey, Jason S. Lee, Kate H. Gartlan, Melody Cheong
The adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD) is known to facilitate caspase-1 activation, which is essential for innate host immunity via the formation of the inflammasome complex, a multiprotein structure respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7145b9fd80a40cc0741b069c6d960d1
https://doi.org/10.1158/2326-6066.c.6550138.v1
https://doi.org/10.1158/2326-6066.c.6550138.v1
Autor:
Geoffrey R. Hill, Steven W. Lane, Mariapia A. Degli-Esposti, Thomas Brocker, Gabrielle T. Belz, Raymond J. Steptoe, Mark J. Smyth, Motoko Koyama, Melody Cheong, Simone A. Minnie, Andrea S. Henden, J. Paulo Martins, Renee J. Robb, Kate H. Gartlan, Daniel J. Browne, Rachel D. Kuns, Kate A. Markey
Supplementary table 1: Supplementary Table 1: Gene expression measured in QIAGEN Apoptosis Array; Supplementary Table 2: Antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042dfc3f266b06f081aef1749f01cb6a
https://doi.org/10.1158/1078-0432.22464882.v1
https://doi.org/10.1158/1078-0432.22464882.v1
Autor:
Geoffrey R. Hill, Steven W. Lane, Mariapia A. Degli-Esposti, Thomas Brocker, Gabrielle T. Belz, Raymond J. Steptoe, Mark J. Smyth, Motoko Koyama, Melody Cheong, Simone A. Minnie, Andrea S. Henden, J. Paulo Martins, Renee J. Robb, Kate H. Gartlan, Daniel J. Browne, Rachel D. Kuns, Kate A. Markey
Purpose: Allogeneic bone marrow transplantation (BMT) provides curative therapy for leukemia via immunologic graft-versus-leukemia (GVL) effects. In practice, this must be balanced against life threatening pathology induced by graft-versus-host disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2311323d00efc28d48e4bbf248a1df81
https://doi.org/10.1158/1078-0432.c.6525849.v1
https://doi.org/10.1158/1078-0432.c.6525849.v1
Autor:
Kate H. Gartlan, Slavica Vuckovic, Karshing Chang, Glen M. Boyle, Vivien R. Sutton, Mark J. Smyth, Melody Cheong, Ping Zhang, Motoko Koyama, Kelli P. A. MacDonald, José Paulo Martins, Christopher E. Andoniou, Joseph A. Trapani, Geoffrey R. Hill, Antiopi Varelias, Greg Kelly, Kate A. Markey, Rachel D. Kuns, Siok-Keen Tey, Mariapia A. Degli-Esposti, Jason Sang Hun Lee, Christian R. Engwerda
Publikováno v:
Cancer Immunology Research. 8:1085-1098
The adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD) is known to facilitate caspase-1 activation, which is essential for innate host immunity via the formation of the inflammasome complex, a multiprotein structure respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2020faa108fc8bfafac1952dcfbe688
https://doi.org/10.1158/2326-6066.cir-19-0653
https://doi.org/10.1158/2326-6066.cir-19-0653
Autor:
Raymond J. Steptoe, Daniel J. Browne, Rachel D. Kuns, Andrea S. Henden, Kate H. Gartlan, J. Paulo Martins, Kate A. Markey, Motoko Koyama, Melody Cheong, Thomas Brocker, Renee J. Robb, Mark J. Smyth, Mariapia A. Degli-Esposti, Simone A. Minnie, Geoffrey R. Hill, Steven W. Lane, Gabrielle T. Belz
Publikováno v:
Clinical Cancer Research. 24:1604-1616
Purpose: Allogeneic bone marrow transplantation (BMT) provides curative therapy for leukemia via immunologic graft-versus-leukemia (GVL) effects. In practice, this must be balanced against life threatening pathology induced by graft-versus-host disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4406524c4676abe247997ae523cf949b
https://doi.org/10.1158/1078-0432.ccr-17-2148
https://doi.org/10.1158/1078-0432.ccr-17-2148
Autor:
Lucie Leveque-El Mouttie, Kylie A. Alexander, Melody Cheong, Kelli P. A. MacDonald, Kate A. Markey, Katie E. Lineburg, Bianca E. Teal, Bruce R. Blazar, Motoko Koyama, Rachel D. Kuns, Andrew D. Clouston, Geoffrey R. Hill, Laetitia Le Texier
Publikováno v:
Blood. 128:794-804
Chronic graft-versus-host disease (cGVHD) is a major cause of late mortality following allogeneic bone marrow transplantation (BMT) and is characterized by tissue fibrosis manifesting as scleroderma and bronchiolitis obliterans. The development of ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd14e0f50fbc7909593442e7b0e6c7e4
https://doi.org/10.1182/blood-2015-11-680876
https://doi.org/10.1182/blood-2015-11-680876
Autor:
Bianca E. Teal, Mark J. Smyth, Katie E. Lineburg, Kate A. Markey, Glen M. Boyle, Shaun R. McColl, Neil C. Raffelt, Antiopi Varelias, Mark D. Bunting, James McCluskey, Motoko Koyama, Jamie Rossjohn, Mary Lor, Brigitta Stockinger, Kelli P. A. MacDonald, Geoffrey R. Hill, Steven W. Lane, Rachel D. Kuns, Stuart D. Olver, Melody Cheong, Michele W.L. Teng, Iain Comerford, Andrew D. Clouston, Kate H. Gartlan
Publikováno v:
Blood. 126:1609-1620
IL-17-producing cells are important mediators of graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (SCT). Here we demonstrate that a distinct CD8(+) Tc17 population develops rapidly after SCT but fails to maintain lineage fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a7a27ac3aa9c2cc314008ec2644b62
https://doi.org/10.1182/blood-2015-01-622662
https://doi.org/10.1182/blood-2015-01-622662