Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Melodie Estabrook"'
Autor:
Girja S. Shukla, Guang-Ping Shen, Christopher J. Murray, Melodie Estabrook, Volker Schellenberger, David N. Krag
Publikováno v:
International Journal of Cancer. 120:2233-2242
A novel β-lactamase scaffold library in which the target-binding moiety is built into the enzyme was generated using phage display technology. The binding element is composed of a fully randomized 8 amino acid loop inserted at position between Y34 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ad7d0c153d642248f3ad0063af8ad6
https://doi.org/10.1002/ijc.22138
https://doi.org/10.1002/ijc.22138
Autor:
Melodie Estabrook, Volker Schellenberger, Pete Gualfetti, Regina Chin, Martin Roberge, Joshua Basler, Amy Liu, Stephanie Wong, M. Harunur Rashid, Lilia Maria Babe, Tom Graycar
Publikováno v:
Protein Engineering, Design and Selection. 19:141-145
CC49 is a clinically validated antibody with specificity for TAG-72, a carbohydrate epitope that is over-expressed and exposed on a large fraction of solid malignancies. We constructed a single chain fragment (scFv) based on CC49 and fused it to beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b970ff0a566f09e4802f3a07c473dc43
https://doi.org/10.1093/protein/gzj012
https://doi.org/10.1093/protein/gzj012
Autor:
David A. Estell, Roopali Rao, Neelam S. Amin, Scott D. Power, Brian F. Schmidt, Bryan P. Fox, Katherine D. Collier, Melodie Estabrook, Gudrun Vogtentanz
Publikováno v:
Protein expression and purification. 68(2)
Replacing the chymotrypsin inhibitory loop of soybean Bowman-Birk inhibitor (sBBI) with a VEGF binding peptide (BBI-AV) significantly reduces the overall purification yield when BBI-AV is produced as a fusion protein in a Bacillussubtilis expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a08ce91e8064c07eb60df6fd25d8ab2
https://pubmed.ncbi.nlm.nih.gov/19686850
https://pubmed.ncbi.nlm.nih.gov/19686850