Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial

Autor: Ruperto N, Lovell DJ, Quartier P, Paz E, Rubio Pérez N, Silva CA, Abud Mendoza C, Burgos Vargas R, Gerloni V, Melo Gomes JA, Saad Magalhães C, Sztajnbok F, Goldenstein Schainberg C, Scheinberg M, Penades IC, Fischbach M, Orozco J, Hashkes PJ, Hom C, Jung L, Lepore L, Oliveira S, Wallace CA, Sigal LH, Block AJ, Covucci A, Martini A, Giannini EH, Paediatric Rheumatology INternational Trials Organization, Pediatric Rheumatology Collaborative Study G.r.o.u.p. Collaborators Huemer C, Meunier BB, Deslandre CJ, Lemelle I, Mouy R, Prieur AM, Horneff G, Huppertz HI, Foeldvari I, Minden K, Ravelli A, Loy A, Cortis E, Falcini F, Nunez AF, Chavez J, Blanco FJ, Hofer M, Eberhard BA, Kivitz A, Punaro M, Olson N, Gardiner L., ALESSIO, MARIA

Publikováno v: The Lancet. 372:383-391

Summary Background Some children with juvenile idiopathic arthritis either do not respond, or are intolerant to, treatment with disease-modifying antirheumatic drugs, including anti-tumour necrosis factor (TNF) drugs. We aimed to assess the safety an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06362ad89ab6cfcc3cfb8fc66dcf1967
https://doi.org/10.1016/s0140-6736(08)60998-8

Síndromes Auto - Inflamatórias

Autor: Melo Gomes, JA, Melo Gomes, S, Conde, M

Publikováno v: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP

As síndromes auto-inflamatórias são constituídas por um grupo heterogéneo de patologias isoladas e caracterizadas ao longo dos últimos 15 anos, graças aos avanços marcados no conhecimento do genoma humano e ao desenvolvimento de técnicas lab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a3d058b67f12c6f189a8def4540aed46
https://hdl.handle.net/10400.17/1547

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Determinants of Discordance Between Criteria for Inactive Disease and Low Disease Activity in Juvenile Idiopathic Arthritis.

Autor: Giancane G; Università degli Studi di Genova and IRCCS, Istituto Giannina Gaslini, Genoa, Italy., Campone C; IRCCS, Istituto Giannina Gaslini, Genoa, Italy., Gicchino MF; IRCCS, Istituto Giannina Gaslini, Genoa, Italy., Alongi A; IRCCS, Istituto Giannina Gaslini, Genoa, Italy., Bava C; Università degli Studi di Genova, Genoa, Italy., Rosina S; IRCCS, Istituto Giannina Gaslini, Genoa, Italy., Boyko Y; Western Ukrainian Specialized Children's Medical Centre, Lviv, Ukraine., Martin N; The Royal Hospital for Children, Glasgow, UK., El Miedany Y; Ain Shams University, Italian Hospital St. Abbassia, Cairo, Egypt., Harjacek M; Clinical Hospital Center Sestre Milosrdnice, Zagreb, Croatia., Hashad S; Tripoli Children's Hospital, Tripoli, Libya., Ioseliani M; M. Iashvili Children's Central Clinic, Tbilisi, Georgia., Burgos-Vargas R; Hospital General de Mexico, Mexico City, Mexico., Joos R; ZNA Jan Palfijn Antwerpen, Antwerp, and Gent University Hospital, Gent, Belgium., Scott C; Red Cross War Memorial Children's Hospital and Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa., Manel M; Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, and University Hospital of Geneva, Geneva, Switzerland., Ayala ZM; Hospital De Clinicas, Universidad Nacional De Asuncion, San Lorenzo, Paraguay., Ekelund M; Ryhov County Hospital, Jonkoping, Sweden., Al-Abrawi S; Royal Hospital, Muscat, Oman., Aiche MF; Hospital of Douera, Alger, Algeria., Norambuena X; Hospital Dr. Exequiel Gonzalez Cortes, Santiago, Chile., Melo-Gomes JA; Instituto Português de Reumatologia, Lisbon, Portugal., Ruperto N; IRCCS, Istituto Giannina Gaslini, Genoa, Italy., Consolaro A; Università degli Studi di Genova and IRCCS, Istituto Giannina Gaslini, Genoa, Italy., Ravelli A; Università degli Studi di Genova, IRCCS, Istituto Giannina Gaslini, Genoa, Italy, and Sechenov First Moscow State Medical University, Moscow, Russian Federation.

Publikováno v: Arthritis care & research [Arthritis Care Res (Hoboken)] 2021 Dec; Vol. 73 (12), pp. 1722-1729. Date of Electronic Publication: 2021 Oct 11.