Výsledky vyhledávání - "Mellodee, White"

Akademický článek

Impact of yellow fever virus envelope protein on wild-type and vaccine epitopes and tissue tropism

Autor: Emily H. Davis, Binbin Wang, Mellodee White, Yan-Jang S. Huang, Vanessa V. Sarathy, Tian Wang, Nigel Bourne, Stephen Higgs, Alan D. T. Barrett

Publikováno v: npj Vaccines, Vol 7, Iss 1, Pp 1-12 (2022)

Abstract The envelope (E) protein of flaviviruses is functionally associated with viral tissue tropism and pathogenicity. For yellow fever virus (YFV), viscerotropic disease primarily involving the liver is pathognomonic for wild-type (WT) infection.

Externí odkaz: https://doaj.org/article/4ee6fe4ce2b546e084696649d0429271

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Impact of yellow fever virus envelope protein on wild-type and vaccine epitopes and tissue tropism

Autor: Emily H, Davis, Binbin, Wang, Mellodee, White, Yan-Jang S, Huang, Vanessa V, Sarathy, Tian, Wang, Nigel, Bourne, Stephen, Higgs, Alan D T, Barrett

Publikováno v: NPJ vaccines. 7(1)

The envelope (E) protein of flaviviruses is functionally associated with viral tissue tropism and pathogenicity. For yellow fever virus (YFV), viscerotropic disease primarily involving the liver is pathognomonic for wild-type (WT) infection. In contr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::24cd42e29ddef752ae81ed15fe45c94d
https://pubmed.ncbi.nlm.nih.gov/35322047

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Japanese encephalitis virus live attenuated vaccine strains display altered immunogenicity, virulence and genetic diversity

Autor: Alan D.T. Barrett, Emily H. Davis, Mellodee White, Steven G. Widen, Jill K. Thompson, Marianne Banks Greenberg, Andrew S. Beck, Nigel Bourne, Li Li

Publikováno v: NPJ Vaccines
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)

Japanese encephalitis virus (JEV) is the etiological agent of Japanese encephalitis (JE). The most commonly used vaccine used to prevent JE is the live-attenuated strain SA14-14-2, which was generated by serial passage of the wild-type (WT) JEV strai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7037762001a78a07ab048389de94318e
https://pubmed.ncbi.nlm.nih.gov/34475404

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Spectrum of activity testing for therapeutics against all four dengue virus serotypes in AG129 mouse models: Proof-of-concept studies with the adenosine nucleoside inhibitor NITD-008

Autor: Gregg N. Milligan, Diana L. Zavala, Richard B. Pyles, Alan D.T. Barrett, Vanessa V. Sarathy, Mellodee White, Nigel Bourne

Publikováno v: Antiviral Research. 154:104-109

Dengue is a mosquito-borne disease of global public health importance caused by four genetically and serologically related viruses (DENV-1 to DENV-4). Efforts to develop effective vaccines and therapeutics for dengue have been slowed by the paucity o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5571cede27e94da93ab5b1122efb54de
https://doi.org/10.1016/j.antiviral.2018.04.012

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Attenuation of Zika Virus by Passage in Human HeLa Cells

Autor: Natalie D. Collins, Li Li, Jaclyn A. Kaiser, Steven G. Widen, M. Banks Greenberg, Vanessa V. Sarathy, Alan D.T. Barrett, Emily H. Davis, Mellodee White, Nigel Bourne

Publikováno v: Vaccines, Vol 7, Iss 3, p 93 (2019)
Vaccines
Volume 7
Issue 3

Zika virus (ZIKV) is a mosquito-borne Flavivirus. Previous studies have shown that mosquito-transmitted flaviviruses, including yellow fever, Japanese encephalitis, and West Nile viruses, could be attenuated by serial passaging in human HeLa cells. &

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652c4b9d6abfb61b725621587b2c929a
https://www.mdpi.com/2076-393X/7/3/93

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Increased Frequency of Virus Shedding by Herpes Simplex Virus 2-Infected Guinea Pigs in the Absence of CD4(+) T Lymphocytes

Autor: Gregg N. Milligan, Hubert Schäfer, Nigel Bourne, Aaron L. Miller, Clarice L. Perry, Brianne N. Banasik, Richard B. Pyles, Mellodee White

Reactivation of herpes simplex virus 2 (HSV-2) results in infection of epithelial cells at the neuro-epithelial junction and shedding of virus at the epithelial surface. Virus shedding can occur in either the presence or absence of clinical disease a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd20e2897cd40b1d9bd5e02fe886b03b
https://europepmc.org/articles/PMC6364026/

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Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2

Autor: Richard B. Pyles, Mellodee White, Brianne N. Banasik, Gregg N. Milligan, Aaron L. Miller, Clarice L. Perry, Nigel Bourne

Publikováno v: Virology. 526

Most analyses of genital immunity to herpes simplex virus type 2 (HSV-2) have been performed in females, consequently immune protection of the male genital epithelium is incompletely understood. We developed a model of male genital HSV-2 infection re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e15791e9c6fdc434c0440b5ccf7d30
https://pubmed.ncbi.nlm.nih.gov/30412859

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Characterization of a murine model of non-lethal, symptomatic dengue virus infection

Autor: Gregg N. Milligan, Jaclyn A. Kaiser, Gerald A. Campbell, Vanessa V. Sarathy, Nigel Bourne, Mellodee White, Alan D.T. Barrett, Li Li

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports

The mosquito-borne disease dengue is caused by four serologically- and genetically-related viruses, termed DENV-1 to DENV-4. Historical setbacks due to lack of human-like mouse models of dengue were partially remedied with characterization of lethal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4d659044f63de54819b1ff215a02d6
https://doi.org/10.1038/s41598-018-22618-w

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