Zobrazeno 1 - 10
of 1 260
pro vyhledávání: '"Melk"'
Autor:
Pengfei Su, Tian Yu, Yingjing Zhang, Hongyun Huang, Moxi Chen, Can Cao, Weiming Kang, Yuqin Liu, Jianchun Yu
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Gastric cancer (GC) stands out as one of the most prevalent malignancies affecting the digestive system, characterized by a substantial incidence rate and mortality. Maternal embryonic leucine zipper kinase (MELK) has been implica
Externí odkaz:
https://doaj.org/article/7460079c322a4b08b7b3c9e72f87c066
Autor:
Sreemita Majumdar, Song-Tao Liu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Maternal Embryonic Leucine Zipper Kinase (MELK) has been studied intensively in recent years due to its overexpression in multiple cancers. However, the cell biology of MELK remains less characterized despite its well-documented association with mito
Externí odkaz:
https://doaj.org/article/0e1d2da26b224c0797b9e773d84fe8fb
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Breast cancer (BC) is a leading cause of global cancer-related mortality in women, necessitating accurate tumor classification for timely intervention. Molecular and histological factors, including PAM50 classification, estrogen receptor α
Externí odkaz:
https://doaj.org/article/71a103b4fd424bdba5771f8600dcacd8
Autor:
Kuoju Cheng, Hao Chen, Bin Chen, Jing Li, Caibo Fan, Huan Yan, Wei Huang, Ting Zhao, Yun Luo, Lei Peng
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101890- (2024)
Background: Circular RNAs (circRNAs) are involved in the progression of colon cancer (CC). This study aimed to examine the role of a new circRNA circ_0101050 in CC. Methods: Dual-luciferase reporter and RNA immunoprecipitation analyses were performed
Externí odkaz:
https://doaj.org/article/7afbe46d5e4c4a69aabb217efc552cee
Autor:
Andrea Fiamma
Publikováno v:
Noctua, Vol 11, Iss 1, Pp 75-155 (2024)
John Schlitpacher (†1482), who was prior of Melk in the 15th century, encouraged both the circulation of manuscripts at his Abbey and their transcription, even in abbreviated form to the benefit of the Abbey School students. This article looks at t
Externí odkaz:
https://doaj.org/article/771360c948874d04a5704d793739e794
Autor:
Cheng, Kuoju a, #, Chen, Hao b, #, Chen, Bin b, Li, Jing b, Fan, Caibo b, Yan, Huan b, Huang, Wei b, Zhao, Ting b, Luo, Yun b, Peng, Lei b, ⁎
Publikováno v:
In Translational Oncology June 2024 44
Akademický článek
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Targeting MELK improves PD-1 blockade efficiency in cervical cancer via enhancing antitumor immunity
Publikováno v:
In Molecular Therapy: Oncology 21 March 2024 32(1)
Targeting MELK improves PD-1 blockade efficiency in cervical cancer via enhancing antitumor immunity
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200759- (2024)
The balance between T helper 1 (Th1) and T helper 2 (Th2) has a critical function in determining intratumoral immune response and anti-PD-1 immunotherapy. The level of maternal embryonic leucine zipper kinase (MELK) is reported to correlate with infi
Externí odkaz:
https://doaj.org/article/58b9d55876ae4e8a91bb87c348d0946c