Výsledky vyhledávání - "Melissa van de Wal"

The decylTPP mitochondria-targeting moiety lowers electron transport chain supercomplex levels in primary human skin fibroblasts

Autor: Elianne P. Bulthuis, Claudia Einer, Felix Distelmaier, Laszlo Groh, Sjenet E. van Emst - de Vries, Els van de Westerlo, Melissa van de Wal, Jori Wagenaars, Richard J. Rodenburg, Jan A.M. Smeitink, Niels P. Riksen, Peter H.G.M. Willems, Merel J.W. Adjobo-Hermans, Hans Zischka, Werner J.H. Koopman

Publikováno v: Free Radical Biology and Medicine, 188, pp. 434-446
Free Radical Biology and Medicine 188 (2022)
Free Radical Biol. Med. 188, 434-446 (2022)
Free Radical Biology and Medicine, 188, 434-446

Attachment of cargo molecules to lipophilic triphenylphosphonium (TPP+) cations is a widely applied strategy for mitochondrial targeting. We previously demonstrated that the vitamin E-derived antioxidant Trolox increases the levels of active mitochon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18dae1c924e2eac5b5e0ad826c47c289
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/253380

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Ndufs4 knockout mouse models of Leigh syndrome: pathophysiology and intervention

Autor: Albert Quintana, Judith Homberg, Merel J. W. Adjobo-Hermans, Mariusz R. Wieckowski, Sander Grefte, Melissa van de Wal, Jaap Keijer, Werner J H Koopman, Evert M. van Schothorst, Clara D.M. van Karnebeek, Tom J.J. Schirris

Publikováno v: Brain, 145, 1, pp. 45-63
Brain, 145, 45-63
Brain, 145(1), 45-63
Brain, 145(1), 45-63. Oxford University Press
Brain 145 (2022) 1

Mitochondria are small cellular constituents that generate cellular energy (ATP) by oxidative phosphorylation (OXPHOS). Dysfunction of these organelles is linked to a heterogeneous group of multisystemic disorders, including diabetes, cancer, ageing-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29f553cee4ad34628f044c06a43ee8b

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