Development and scale-up of rVSV-SARS-CoV-2 vaccine process using single use bioreactor

Autor: Christopher Ton, Victoria Stabile, Elizabeth Carey, Adam Maraikar, Travis Whitmer, Samantha Marrone, Nelson Lee Afanador, Igor Zabrodin, Greeshma Manomohan, Melissa Whiteman, Carl Hofmann

Publikováno v: Biotechnology Reports, Vol 37, Iss , Pp e00782- (2023)

The outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes the Coronavirus Disease 2019 (COVID-19) has spread through the globe at an alarming speed. The disease has become a global pandemic affecting millions

Externí odkaz: https://doaj.org/article/4fd0a7637b2d4926b0ed7090e3c16f92

Melissa Whiteman: Storm Painter.

Autor: Wan, Julie¹

Publikováno v: Weatherwise. Mar/Apr2009, Vol. 62 Issue 2, p56-57. 2p. 2 Color Photographs.

A West Nile Virus NS4B P38G mutant strain induces adaptive immunity via TLR7-MyD88-dependent and independent signaling pathways. (P4317)

Autor: Guorui Xie, Thomas Welte, Jia Wang, Ye Wang, Melissa Whiteman, Jason Wicker, Vandana Saxena, Yingzi Cong, Alan Barrett, Tian Wang

Publikováno v: The Journal of Immunology. 190:123.22-123.22

West Nile virus (WNV)- induced neurological disease has become a public health concern. No vaccines have been approved for human use. We have previously shown that an attenuated WNV, the nonstructural (NS) 4B-P38G mutant, induced stronger innate cyto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::789947560a7619215c6c2868e2f7d88a
https://doi.org/10.4049/jimmunol.190.supp.123.22

Development and scale-up of rVSV-SARS-CoV-2 vaccine process using single use bioreactor.

Autor: Ton C; Vaccine Process Development, Merck & Co., Inc., West Point, Pennsylvania, 19486, United States., Stabile V; Vaccine Process Development, Merck & Co., Inc., West Point, Pennsylvania, 19486, United States., Carey E; Vaccine Process Development, Merck & Co., Inc., West Point, Pennsylvania, 19486, United States., Maraikar A; Bioprocess Clinical Manufacturing & Technology, Merck & Co., Inc., West Point, Pennsylvania, 19486, United States., Whitmer T; Bioprocess Drug Substance Commercialization, Merck & Co., Inc., West Point, Pennsylvania, 19486, United States., Marrone S; Vaccine Process Development, Merck & Co., Inc., West Point, Pennsylvania, 19486, United States., Afanador NL; Biostatistics and Research Decision Sciences, Merck & Co., Inc., West Point, Pennsylvania, 19486, United States., Zabrodin I; Vaccine Process Development, Merck & Co., Inc., West Point, Pennsylvania, 19486, United States., Manomohan G; Currently at GlaxoSmithKline plc, King of Prussia, Pennsylvania, 19406, United States., Whiteman M; Analytical Research & Development, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Hofmann C; Analytical Research & Development, Merck & Co., Inc., West Point, Pennsylvania 19486, United States.

Publikováno v: Biotechnology reports (Amsterdam, Netherlands) [Biotechnol Rep (Amst)] 2023 Mar; Vol. 37, pp. e00782. Date of Electronic Publication: 2023 Jan 16.