Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Melissa V. Fernandez"'
Autor:
Carmen A. Buttler, Nairi Pezeshkian, Melissa V. Fernandez, Jesse Aaron, Sofya Norman, Eric O. Freed, Schuyler B. van Engelenburg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
HIV particles contain a relatively low amount of viral envelope (Env), but underlying packaging mechanisms are poorly understood. Here, the authors use superresolution microscopy and show that Env distribution is biased toward the necks of cell-assoc
Externí odkaz:
https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d8
Autor:
Melissa V. Fernandez-de Céspedes, Huxley K. Hoffman, Hannah Carter, Lacy M. Simons, Lwar Naing, Sherimay D. Ablan, David A. Scheiblin, Judd F. Hultquist, Schuyler B. van Engelenburg, Eric O. Freed
Publikováno v:
Journal of Virology. 96
The incorporation of the HIV-1 envelope (Env) glycoproteins, gp120 and gp41, into virus particles is critical for virus infectivity. gp41 contains a long cytoplasmic tail that has been proposed to interact with host cell factors, including the traffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93a9e531c1bc5402f8d054a9ae039de7
https://doi.org/10.1128/jvi.00876-22
https://doi.org/10.1128/jvi.00876-22
Akademický článek
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Autor:
Melissa V. Fernandez, Eric O. Freed
Publikováno v:
Viruses, Vol 10, Iss 11, p 613 (2018)
Recent developments in defining the role of the lentiviral envelope glycoprotein (Env) cytoplasmic tail (CT) in Env trafficking and incorporation into virus particles have advanced our understanding of viral replication and transmission. To stimulate
Externí odkaz:
https://doaj.org/article/7d09d38a7a964ef3989ed44f968b6ab6
Autor:
Huxley K. Hoffman, Schuyler B. van Engelenburg, Eric O. Freed, Melissa V. Fernandez, Nicholas S. Groves
Publikováno v:
The Journal of Biological Chemistry
The endosomal sorting complexes required for transport (ESCRT) machinery drives membrane scission for diverse cellular functions that require budding away from the cytosol, including cell division and transmembrane receptor trafficking and degradatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047c3ce3f3603635f8540cc0a5960cb8
https://doi.org/10.1074/jbc.ra119.009372
https://doi.org/10.1074/jbc.ra119.009372
Autor:
Melissa V. Fernandez, Eric O. Freed, Schuyler B. van Engelenburg, Nairi Pezeshkian, Huxley K. Hoffman, Philip R. Tedbury
Publikováno v:
J Virol
HIV-1 encodes an envelope glycoprotein (Env) that contains a long cytoplasmic tail (CT) harboring trafficking motifs implicated in Env incorporation into virus particles and viral transmission. In most physiologically relevant cell types, the gp41 CT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4fb93a626d2c3f374febc503ca5426
https://europepmc.org/articles/PMC7654282/
https://europepmc.org/articles/PMC7654282/
Autor:
David A Scheiblin, Jennifer A Simmons, Eric O. Freed, Sherimay D. Ablan, Melissa V. Fernandez, Lwar N Naing
Publikováno v:
Proceedings, Vol 50, Iss 17, p 17 (2020)
HIV-1 encodes an envelope glycoprotein complex (Env) containing a long cytoplasmic tail (CT) harboring trafficking motifs implicated in Env incorporation into virions. Although the requirement for the Env CT in viral transmission is known, the precis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835b76f82598cbde97b14acde8501dce
https://www.mdpi.com/2504-3900/50/1/17
https://www.mdpi.com/2504-3900/50/1/17
Autor:
Jesse Aaron, Schuyler B. van Engelenburg, Melissa V. Fernandez, Nairi Pezeshkian, Carmen A. Buttler, Sofya Norman, Eric O. Freed
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications
Nature Communications
Human immunodeficiency virus type 1 (HIV-1) assembly occurs on the inner leaflet of the host cell plasma membrane, incorporating the essential viral envelope glycoprotein (Env) within a budding lattice of HIV-1 Gag structural proteins. The mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c6f9da7e564d6ffcbb15129ddb9899
https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d8
https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d8
Autor:
Krista A. Delviks-Frankenberry, David A Scheiblin, Eric O. Freed, Christine Happel, Melissa V. Fernandez, Vinay K. Pathak
Publikováno v:
J Virol
The MT-4 human T-cell line expresses HTLV-1 Tax and is permissive for replication of an HIV-1 gp41 mutant lacking the cytoplasmic tail. MT-4 cells (lot 150048), distributed by the NIH AIDS Reagent Program (NIH-ARP), were found to be Tax deficient and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e473d96fcd90d4b026e911c8410ae8c0
https://europepmc.org/articles/PMC6880167/
https://europepmc.org/articles/PMC6880167/