Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Melissa Umphlett"'
Autor:
Katherine Ember, Frédérick Dallaire, Arthur Plante, Guillaume Sheehy, Marie-Christine Guiot, Rajeev Agarwal, Rajeev Yadav, Alice Douet, Juliette Selb, Jean Philippe Tremblay, Alex Dupuis, Eric Marple, Kirk Urmey, Caroline Rizea, Armand Harb, Lily McCarthy, Alexander Schupper, Melissa Umphlett, Nadejda Tsankova, Frédéric Leblond, Constantinos Hadjipanayis, Kevin Petrecca
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Safe and effective brain tumor surgery aims to remove tumor tissue, not non-tumoral brain. This is a challenge since tumor cells are often not visually distinguishable from peritumoral brain during surgery. To address this, we conducted a mu
Externí odkaz:
https://doaj.org/article/95de17ab5b1d48a395c68a261f12ee61
Autor:
Meenakshi Vij, Benjamin B. Cho, Raquel T. Yokoda, Omid Rashidipour, Melissa Umphlett, Timothy E. Richardson, Nadejda M. Tsankova
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Molecular characterization of gliomas has uncovered genomic signatures with significant impact on tumor diagnosis and prognostication. CDKN2A is a tumor suppressor gene involved in cell cycle control. Homozygous deletion of the CDKN2A/B locu
Externí odkaz:
https://doaj.org/article/c577778d01c944589b9ed8e594c91f0b
Autor:
Melissa Umphlett, Stephanie Shea, Jessica Tome-Garcia, Yizhou Zhang, Adilia Hormigo, Mary Fowkes, Nadejda M. Tsankova, Raymund L. Yong
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Glioblastoma (GBM) is a highly malignant brain neoplasm with poor survival. Despite its aggressive nature, metastatic spread of GBM is identified only rarely. While the molecular alterations associated with GBM and its subtypes ar
Externí odkaz:
https://doaj.org/article/55a688632fdb4857adb89bd21cccb2a8
Autor:
Jonathan T, Dullea, Vikram, Vasan, John W, Rutland, Corey M, Gill, Danielle, Chaluts, Daniel, Ranti, Ethan, Ellis, Varun, Subramanium, Annie, Arrighi-Allisan, Yayoi, Kinoshita, Russell B, McBride, Joshua, Bederson, Michael, Donovan, Robert, Sebra, Melissa, Umphlett, Raj K, Shrivastava
Publikováno v:
Oncoscience. 9:70-81
Meningiomas are common intracranial tumors with variable prognoses not entirely captured by commonly used classification schemes. We sought to determine the relationship between meningioma mutations and oncologic outcomes using a targeted next-genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6e2a823588c9ce82332bb59dfe2299
https://doi.org/10.18632/oncoscience.570
https://doi.org/10.18632/oncoscience.570
Autor:
Meenakshi Vij, Raquel T Yokoda, Omid Rashidipour, Ivy Tran, Varshini Vasudevaraja, Matija Snuderl, Raymund L Yong, William S Cobb, Melissa Umphlett, Jamie M Walker, Nadejda M Tsankova, Timothy E Richardson
Publikováno v:
Neuro-Oncology Advances.
Background IDH mutations are thought to represent an early oncogenic event in glioma evolution, found with high penetrance across tumor cells, however in rare cases IDH mutation may exist only in a small subset of the total tumor cells (subclonal IDH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::131c398cb3d397b4648a7c90caf0c8a1
https://doi.org/10.1093/noajnl/vdad069
https://doi.org/10.1093/noajnl/vdad069
Autor:
Matthew T. Carr, Gianina C. Hernandez-Marquez, Meenakshi Vij, Xing Chin, Bradley N. Delman, Melissa Umphlett, Isabelle M. Germano
Publikováno v:
World Neurosurgery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfc842c79ffb86502cd28f2196c3f1f2
https://doi.org/10.1016/j.wneu.2023.03.031
https://doi.org/10.1016/j.wneu.2023.03.031
Autor:
Vikram Vasan, Jonathan T. Dullea, Alex Devarajan, Muhammad Ali, John W. Rutland, Corey M. Gill, Yayoi Kinoshita, Russell B. McBride, Paul Gliedman, Joshua Bederson, Michael Donovan, Robert Sebra, Melissa Umphlett, Raj K. Shrivastava
Publikováno v:
Journal of neuro-oncology.
High grade meningiomas have a prognosis characterized by elevated recurrence rates and radiation resistance. Recent work has highlighted the importance of genomics in meningioma prognostication. This study aimed to assess the relationship between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2378ddae35bcc1ff55dd7fad29444284
https://pubmed.ncbi.nlm.nih.gov/36436149
https://pubmed.ncbi.nlm.nih.gov/36436149
Autor:
Danielle Chaluts, Jonathan T. Dullea, Muhammad Ali, Vikram Vasan, Alex Devarajan, John W. Rutland, Corey M. Gill, Ethan Ellis, Yayoi Kinoshita, Russell B. McBride, Joshua Bederson, Michael Donovan, Robert Sebra, Melissa Umphlett, Raj K. Shrivastava
Publikováno v:
Journal of cancer research and clinical oncology.
The oncologic outcomes for atypical meningiomas can be poor. Generally, patients that have had a prior recurrence have a substantially elevated risk of a future recurrence. Additionally, certain tumor genomic profiles have been shown as markers of po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231258170eb8dde46a8ffa8ab947eb14
https://pubmed.ncbi.nlm.nih.gov/36348021
https://pubmed.ncbi.nlm.nih.gov/36348021
Autor:
Melissa Umphlett, Khawaja Hasan Bilal, Michael L Martini, Abigail K Suwala, Sadhna Ahuja, Omid Rashidipour, Isabelle Germano, Matija Snuderl, Peter Morgenstern, Nadejda M Tsankova
Publikováno v:
Neuro-oncology advances. 4(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051a8992c6cd6c32bfed5f2551ba304a
https://pubmed.ncbi.nlm.nih.gov/35669011
https://pubmed.ncbi.nlm.nih.gov/35669011
Autor:
Margaret Pain, Joshua B. Bederson, Melissa Umphlett, Yayoi Kinoshita, Michael J. Donovan, John W. Rutland, Joshua Loewenstern, Mary Fowkes, Raj K. Shrivastava, Hanane Arib, Corey M. Gill, Russell B. McBride, Robert Sebra
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 147:3431-3440
While SWI/SNF chromatin remodeling complex alterations occur in approximately 20% of cancer, the frequency and potential impact on clinical outcomes in meningiomas remains to be comprehensively elucidated. A large series of 255 meningiomas from a sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a53c736fd216637a84ff8e1468751f4a
https://doi.org/10.1007/s00432-021-03586-7
https://doi.org/10.1007/s00432-021-03586-7