Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Melissa Stern"'
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
Non-suicidal self-injury (NSSI) has consistently been associated with self-reported difficulties in emotion reactivity and the regulation of negative emotions; however, less is known about the accuracy of these self-reports or the reactivity and regu
Externí odkaz:
https://doaj.org/article/3092eddc506c41c983c2188ba64a77c9
Akademický článek
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Publikováno v:
Psychological Reports. :003329412311801
In trying to better understand why certain individuals self-injure, researchers have proposed high emotional reactivity for negative emotions may influence vulnerabilities and predispose individuals to react to stressful situations in a dysregulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0072fec22658f4545d566b2b9c2cb9c3
https://doi.org/10.1177/00332941231180118
https://doi.org/10.1177/00332941231180118
Autor:
Laurel March, Jill Jarvie, Juliette Mullin, Jennifer Hopping-Winn, Melissa Stern, Michelle Caughey
Publikováno v:
Journal of Palliative Medicine. 21:541-545
Since 2013, Kaiser Permanente Northern California has engaged in a systematic effort to elicit, document, and honor the care preferences of patients as they near the end of life. This is done through its Advanced Steps program, in which selected pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02eec477656c4b4043628c80dd73a070
https://doi.org/10.1089/jpm.2017.0317
https://doi.org/10.1089/jpm.2017.0317
Autor:
Ryan G. Kruger, Junya Qu, Dai-Shi Su, Helai P. Mohammad, Melissa B. Pappalardi, Patricia A. Elkins, Alan P. Graves, Dirk A. Heerding, William G. Bonnette, Joelle Lorraine Burgess, Juan I. Luengo, Jenny Zeng, Beth Anne Knapp-Reed, Mark J. Schulz, Alexander Joseph Reif, Jeffrey D. Carson, Raman P. Nagarajan, Caretha L. Creasy, Chuck W Blackledge, Kristen Wong, Melissa Stern, Charles F. McHugh, Hongyi Yu, Liping Wang
Publikováno v:
ACS Med Chem Lett
[Image: see text] We report herein the discovery of isoxazole amides as potent and selective SET and MYND Domain-Containing Protein 3 (SMYD3) inhibitors. Elucidation of the structure–activity relationship of the high-throughput screening (HTS) lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83a077b5e8d3e9547f467b0db76acd2
https://pubmed.ncbi.nlm.nih.gov/32071679
https://pubmed.ncbi.nlm.nih.gov/32071679
Autor:
Juanita Lopez, Jane N. Winter, Caretha L. Creasy, Jemma Longley, Timothy A. Yap, Thierry Horner, Jean-Marie Michot, Teodora Pene Dumitrescu, Lisa Giulino-Roth, Xiaowei Wang, Michael T. McCabe, Peter Johnson, Melissa Stern, John P. Leonard, Ahmed Khaled, Choon K. Oh, Jennifer Carver, Steve Frey, Arindam Dhar, Vincent Ribrag
Publikováno v:
Clin Cancer Res
Purpose: Enhancer of zeste homolog 2 (EZH2) activity is dysregulated in many cancers. Patients and Methods: This phase I study determined the safety, maximum-tolerated dose (MTD), pharmacokinetics, and pharmacodynamics of the intravenously administer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efeddcf8b4dd68b765265a60f67caa02
https://eprints.soton.ac.uk/436432/
https://eprints.soton.ac.uk/436432/
Autor:
Melissa Stern
Publikováno v:
The Permanente Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bbf6ce9a26245cb0a18769b16a190fe
https://doi.org/10.7812/tpp/18-071-39
https://doi.org/10.7812/tpp/18-071-39
Autor:
Quang Truong, Conrad E. Raab, Michael J. Lyman, Andrew H. Latham, Haihong Fan, Eileen S. Walsh, Marissa Vavrek, Robert M. Garbaccio, Eric Kemp, Marc Abrams, Erin N. Guidry, Tao Pei, Steven L. Colletti, Laura Sepp-Lorenzino, Edward J. Carlini, Carol Bason, Melissa Stern, J. Michael Williams, Eric D. Soli, Rob S. Burke, Mihir Patel, Jun H. Heo, Brian A. Carr, Stephanie Young, Jacob H. Waldman, Sean Riley, Nicole T. Pudvah, Louis S. Crocker, Bonnie J. Howell, Sergey Pechenov, Steven J. Staskiewicz, Sheri Smith, Marina Busuek, Rubina G. Parmar, Stephanie E. Barrett, Anthony Leone, Robert A. Kowtoniuk
Publikováno v:
Journal of Controlled Release. 183:124-137
The greatest challenge standing in the way of effective in vivo siRNA delivery is creating a delivery vehicle that mediates a high degree of efficacy with a broad therapeutic window. Key structure-activity relationships of a poly(amide) polymer conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bc6874b79ed8d0c0f604e7f90890f9
https://doi.org/10.1016/j.jconrel.2014.03.028
https://doi.org/10.1016/j.jconrel.2014.03.028
Autor:
Edward Keough, Suzie Yeh, Mike Lyman, Ken Koeplinger, Ed Carlini, Charles D. Thompson, Jeff Roberts, Marian E. Gindy, Melissa Stern, Scott Fauty, Mei Ou, Yan Xu, Elizabeth Mahan, Conrad E. Raab, Yi Wang, Jerome Hochman, Rena Zhang, Don Slaughter
Publikováno v:
Molecular Pharmaceutics. 11:1424-1434
Effective delivery of small interfering RNA (siRNA) requires efficient cellular uptake and release into cytosol where it forms an active complex with RNAi induced silencing complex (RISC). Despite rapid developments in RNAi therapeutics, improvements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9336458e9196c53535274f85ff505c96
https://doi.org/10.1021/mp400584h
https://doi.org/10.1021/mp400584h
Autor:
Victoria Ortiz, Melissa C. Musso, Olena Barbash, Christopher L. Carpenter, Lijoy K. Mathew, Xi-Ping Zhang, Charles F. McHugh, Anastasia Wyce, Peter J. Tummino, Susan Korenchuk, Daniel J. Felitsky, Melissa Stern, Ramona Plant, Jeanne J. Matteo, Yan Degenhardt, Sakina Khaku, Kathryn Keenan
Publikováno v:
Cancer Research. 76:4709-4709
BET (bromodomain and extra-terminal) family proteins are epigenetic readers that modulate expression genes involved in cell growth and oncogenesis. Selective small molecule BET inhibitors, such as the GSK I-BETs (I-BET762, I-BET151), abrogate binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::453cac0112661846f672903ab86a9392
https://doi.org/10.1158/1538-7445.am2016-4709
https://doi.org/10.1158/1538-7445.am2016-4709