Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Melissa Sandahl"'
Autor:
Miriam H. Levy, Allen E. Eckhardt, Vamsee K. Pamula, Germaine J. Siew, Roxana Jalili, Deborah J. Boles, Peter B. Griffin, Lisa Perkins, Prasanna Thwar, Michael G. Pollack, Richard B. Fair, Melissa Sandahl, Arjun Sudarsan, Jeremy Rouse, Jonathan L. Benton, Vijay Srinivasan
Publikováno v:
Analytical Chemistry. 83:8439-8447
The feasibility of implementing pyrosequencing chemistry within droplets using electrowetting-based digital microfluidics is reported. An array of electrodes patterned on a printed-circuit board was used to control the formation, transportation, merg
Publikováno v:
Molecular Endocrinology. 22:2307-2321
Differentiation of mammary epithelium in vivo requires signaling through prolactin and ErbB4/HER4-dependent mechanisms. Although stimulation of either the prolactin receptor or ErbB4/HER4 results in activation of the transcription factor signal trans
Autor:
Peter B. Griffin, Mark Horowitz, J. A. Moore, George M. Church, Srikoundinya Punnamaraju, Mohsen Nemat-Gorgani, Allen E. Eckhardt, Melissa Sandahl, Richard B. Fair, Andrew C. Madison, Frederic Vigneault, Michael G. Pollack
Publikováno v:
Biomicrofluidics. 11:014110
This paper reports on the use of a digital microfluidic platform to perform multiplex automated genetic engineering (MAGE) cycles on droplets containing Escherichia coli cells. Bioactivated magnetic beads were employed for cell binding, washing, and
Autor:
Elizabeth F. Redente, H. Shelton Earp, Kristen M. Jacobsen, Anne M. Wofford, Karen E. Strunk, Deborah DeRyckere, Melissa Sandahl, Rebecca S. Cook, Jamie C. Stanford, Anne L. Prieto, Douglas K. Graham, Debra Hunter
MerTK, a receptor tyrosine kinase (RTK) of the TYRO3/AXL/MerTK family, is expressed in myeloid lineage cells in which it acts to suppress proinflammatory cytokines following ingestion of apoptotic material. Using syngeneic mouse models of breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0004759273e5f98bfc2b9b3f856d4c
Autor:
Karen E. Strunk, Carty Husted, Melissa Sandahl, Rebecca S. Muraoka-Cook, Leah C. Miraglia, Debra Hunter, H. Shelton Earp, Lewis A. Chodosh, Klaus Elenius
Publikováno v:
Molecular and cellular biology. 29(18)
Data concerning the prognostic value of ErbB4 in breast cancer and effects on cell growth have varied in published reports, perhaps due to the unknown signaling consequences of expression of the intracellular proteolytic ErbB4 s80(HER4) fragment or d
Autor:
Rebecca S. Muraoka-Cook, Azeddine Atfi, Melissa Sandahl, Debra Hunter, H. Shelton Earp, Shu Mang Feng, Laura S. Caskey, Keiji Miyazawa
In general, epidermal growth factor receptor family members stimulate cell proliferation. In contrast, at least one HER4 isoform, JM-a/Cyt1, inhibits cell growth after undergoing a two-step proteolytic cleavage that first produces a membrane-anchored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b5b9d5d9cb459862a44ba21851b832
https://europepmc.org/articles/PMC2630679/
https://europepmc.org/articles/PMC2630679/
Autor:
Rebecca S. Muraoka-Cook, Carty Husted, H. Shelton Earp, Debra Hunter, Melissa Sandahl, William A. Rearick, Leah C. Miraglia, Karen E. Strunk
Publikováno v:
Cancer research. 67(14)
Heregulin-mediated activation of HER4 initiates receptor cleavage (releasing an 80-kDa HER4 intracellular domain, s80HER4, containing nuclear localization sequences) and results in G2-M delay by unknown signaling mechanisms. We report herein that s80
Autor:
H. Shelton Earp, Karen E. Strunk, Rebecca S. Muraoka-Cook, Wesley McCall, Kenneth H. Cowan, Magdalene K. Sgagias, Melissa Sandahl, Laura S. Caskey, Debra Hunter, Carty Husted, Carolyn I. Sartor, William A. Rearick
Publikováno v:
Molecular and cellular biology. 26(17)
HER4 expression in human breast cancers correlates with a positive prognosis. While heregulin inhibits the growth of HER4-positive breast cancer cells, it does so by undefined mechanisms. We demonstrate that heregulin-induced HER4 activity inhibits c
Autor:
Rebecca S. Muraoka-Cook, Leah C. Miraglia, Shu Mang Feng, Klaus Elenius, H. Shelton Earp, Melissa Sandahl, Carty Husted, Debra Hunter
Differentiation of mammary epithelium in vivo requires signaling through prolactin- and ErbB4/HER4-dependent mechanisms; how these pathways intersect is unknown. We show herein that HC11 mouse mammary cells undergo ErbB4-dependent lactational differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39af53e2ec8653103a5cbc674df7a736
Publikováno v:
BMC Developmental Biology
BMC Developmental Biology, Vol 10, Iss 1, p 122 (2010)
BMC Developmental Biology, Vol 10, Iss 1, p 122 (2010)
Background Mammary glands harbor a profound burden of apoptotic cells (ACs) during post-lactational involution, but little is known regarding mechanisms by which ACs are cleared from the mammary gland, or consequences if this process is interrupted.