Výsledky vyhledávání - "Melissa S, Samuel"

Akademický článek

Oral fluid testing can be used to monitor xenotransplant donor herds for porcine cytomegalovirus/roseolovirus status

Autor: Susan K. Schommer, Melissa S. Samuel, Kristin M. Whitworth, Addison K. Byrne, Kevin D. Wells, Randall S. Prather

Publikováno v: Frontiers in Veterinary Science, Vol 11 (2024)

A major concern of xenotransplantation is that donor organs may be a source of pathogens. One pathogen in particular, porcine cytomegalovirus (PCMV), a porcine roseolovirus (PRV), is thought to result in donor organ failure in an immunosuppressed sta

Externí odkaz: https://doaj.org/article/d914359dafc74ef8901f3522a2e07bb2

Zobrazit plný text záznamu

Akademický článek

Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract Senecavirus A (SVA) is a cause of vesicular disease in pigs, and infection rates are rising within the swine industry. Recently, anthrax toxin receptor 1 (ANTXR1) was revealed as the receptor for SVA in human cells. Herein, the role of ANTXR

Externí odkaz: https://doaj.org/article/2a7f2ae4bfcc4e1b94db3d06a2d64dec

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Serologic titers to Leptospira in vaccinated pigs and interpretation for surveillance

Autor: Susan K. Schommer, Nicholas Harrison, Michael Linville, Melissa S. Samuel, Sabrina L. Hammond, Kevin D. Wells, Randall S. Prather

Publikováno v: PLoS ONE, Vol 16, Iss 11 (2021)

Diagnosis and surveillance of pathogenic Leptospira is difficult as organisms may be intermittently shed and in small numbers. Therefore, serologic testing by the microscopic agglutination test (MAT) is the primary screening method for leptospirosis.

Externí odkaz: https://doaj.org/article/da7ac4a940f04b69b4a8516274d8787d

Zobrazit plný text záznamu

Akademický článek

A porcine model of phenylketonuria generated by CRISPR/Cas9 genome editing

Publikováno v: JCI Insight, Vol 5, Iss 20 (2020)

Phenylalanine hydroxylase–deficient (PAH-deficient) phenylketonuria (PKU) results in systemic hyperphenylalaninemia, leading to neurotoxicity with severe developmental disabilities. Dietary phenylalanine (Phe) restriction prevents the most deleteri

Externí odkaz: https://doaj.org/article/25a4c7bc5404441d96bc2b097f4c68db

Zobrazit plný text záznamu

Chloride channel accessory 1 gene deficiency causes selective loss of mucus production in a new pig model

Autor: Shamus P. Keeler, Jennifer Yantis, Benjamin J. Gerovac, Samuel L. Youkilis, Stephanie Podgorny, Dailing Mao, Yong Zhang, Kristin M. Whitworth, Bethany Redel, Melissa S. Samuel, Kevin D. Wells, Randall S. Prather, Michael J. Holtzman

Publikováno v: Am J Physiol Lung Cell Mol Physiol

Morbidity and mortality of respiratory diseases are linked to airway obstruction by mucus but there are still no specific, safe, and effective drugs to correct this phenotype. The need for better treatment requires a new understanding of the basis fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94d469409d87497a9fac037ed67bc26
https://europepmc.org/articles/PMC9142155/

Zobrazit plný text záznamu

Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection

Publikováno v: Scientific reports. 12(1)

Senecavirus A (SVA) is a cause of vesicular disease in pigs, and infection rates are rising within the swine industry. Recently, anthrax toxin receptor 1 (ANTXR1) was revealed as the receptor for SVA in human cells. Herein, the role of ANTXR1 as a re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22fcc6361fa29d91ad9fa64ebe835b5
https://pubmed.ncbi.nlm.nih.gov/35322150

Zobrazit plný text záznamu

Akademický článek

Disruption of Mitochondrion-To-Nucleus Interaction in Deceased Cloned Piglets.

Autor: Joonghoon Park, Liangxue Lai, Melissa S Samuel, David Wax, Randall S Prather, Xiuchun Tian

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0129378 (2015)

Most animals produced by somatic cell nuclear transfer (SCNT) are heteroplasmic for mitochondrial DNA (mtDNA). Oxidative phosphorylation (OXPHOS) in clones therefore requires the coordinated expression of genes encoded by the nuclear DNA and the two

Externí odkaz: https://doaj.org/article/801ee70e1e9140ff9fbc862dadbafa76

Zobrazit plný text záznamu

Use of single stranded targeting DNA or negative selection does not further increase the efficiency of a GGTA1 promoter trap

Autor: Benjamin P, Beaton, Jiude, Mao, Clifton N, Murphy, Melissa S, Samuel, Randall S, Prather, Kevin D, Wells

Publikováno v: Journal of molecular cloninggenetic recombination. 2(1)

Although several techniques have been developed to create gene knockouts in pigs, homologous recombination will continue to be required for site-specific genome modifications that are more sophisticated than gene disruption (base changes, domain exch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e54a6e3349f618389991f386f963d9cd
https://pubmed.ncbi.nlm.nih.gov/25309937

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání