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pro vyhledávání: '"Melissa R. Potter"'
Publikováno v:
Infection and Immunity. 68:5603-5609
Lyme disease is a tick-transmitted infection caused by the spirochete Borrelia burgdorferi (17, 25, 42). Illness in humans can be successfully treated with antibiotics; however, in the absence of treatment, arthritis, carditis, neurological complicat
Autor:
Melissa R. Potter, David T. Denhardt, Janis J. Weis, Randall J. Roper, Cory Teuscher, John H. Weis, Susan R. Rittling
Several genetic loci in the mouse have been identified that regulate the severity of Lyme arthritis. The region of chromosome 5 including the osteopontin (OPN) gene (Opn) has been identified in intercross populations of C3H/HeN × C57BL/6 and C3H/HeJ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d53d9f3472971ef42e5da96f7b66945
https://europepmc.org/articles/PMC127811/
https://europepmc.org/articles/PMC127811/
Autor:
D Fairbairn, K S Weber, C B Green, Cory Teuscher, Ying Ma, James F. Zachary, Rebecca W. Doerge, B A McCracken, Russell J. Butterfield, Janis J. Weis, Randall J. Roper, Melissa R. Potter
Publikováno v:
Genes and immunity. 2(7)
C3H/He mice infected with Borrelia burgdorferi develop severe arthritis and are high antibody responders, while infected C57BL/6 and BALB/c mice develop mild arthritis and less robust humoral responses. Genetic analysis using composite interval mappi