Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Melissa R. Dent"'
Autor:
Delfin Rodriguez-Leyva, Paramjit S. Tappia, Melissa R. Dent, Harjot K. Saini-Chohan, Naranjan S. Dhalla, Vijayan Elimban
Publikováno v:
Cardiovascular Research. 81:429-438
It is commonly held that cardiac remodelling, represented by changes in muscle mass, size, and shape of the heart, explains the progression of congestive heart failure (CHF). However, this concept does not provide any clear information regarding the
Alterations in both death and survival signals for apoptosis in heart failure due to volume overload
Publikováno v:
Journal of Molecular and Cellular Cardiology. 43:726-732
Heart failure is known to be associated with an increase in cardiomyocyte apoptosis; however, neither its occurrence nor the mechanisms involved in hearts failing due to volume overload are completely understood. This study examined some of the signa
Autor:
Melissa R. Dent, Andrea P. Babick, Hope WeilerH. Weiler, Paramjit S. Tappia, Nina Aroutiounova
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 85:465-475
In an earlier study, we showed that dietary conjugated linoleic acid (CLA) isomers can exert differential effects on heart function in male and female rats, but the underlying mechanisms for these actions are not known. Cardiomyocyte Ca2+ cycling is
Autor:
Girma Asemu, Paramjit S. Tappia, Tushi Singal, Rabban Mangat, Melissa R. Dent, Naranjan S. Dhalla
Publikováno v:
Future Lipidology. 1:701-717
Myocardial phospholipases hydrolyze specific membrane phospholipids to generate important lipid-signaling molecules that are known to influence cardiac function. It is likely that changes in these phospholipases and their related signaling events may
Publikováno v:
Journal of Cellular and Molecular Medicine
Because the left ventricular (LV) hypertrophy due to volume overload induced by arteriovenous (AV) shunt was associated with an increase in phospholipase C (PLC) isozyme mRNA levels, PLC is considered to be involved in the development of cardiac hype
Autor:
Rajat Sethi, Naranjan S. Dhalla, Melissa R. Dent, Paramjit S. Tappia, Ramesh K. Goyal, Judit Barta
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 11:31-45
It is now well known that congestive heart failure (CHF) is invariably associated with cardiac hypertrophy, and changes in the shape and size of cardiomyocytes (cardiac remodeling) are considered to explain cardiac dysfunction in CHF. However, the me
Publikováno v:
British Journal of Nutrition. 93:471-477
An adverse environmental experience of the growing fetus may lead to permanent changes in the structure and function of organs that may predispose the individual to chronic diseases in later life; however, nothing is known about the occurrence and me
Publikováno v:
Journal of Cellular and Molecular Medicine. 8:526-536
The phospholipase D (PLD) associated with the cardiac sarcolemmal (SL) membrane hydrolyses phosphatidylcholine to produce phosphatidic acid, an important phospholipid signaling molecule known to influence cardiac function. The present study was under
Publikováno v:
Cardiac Adaptations ISBN: 9781461452027
Cardiac hypertrophy is an adaptive response of the heart to hemodynamic overload, during which terminally differentiated cardiomyocytes increase in size without undergoing cell division. Although the hypertrophic response may serve to maintain cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b59b3e4055b47a8ad66ff7745c191802
https://doi.org/10.1007/978-1-4614-5203-4_10
https://doi.org/10.1007/978-1-4614-5203-4_10
Publikováno v:
Journal of cellular physiology. 227(8)
This study was undertaken to determine gender related changes in different components of β-adrenoceptor (β-AR) system in response to arteriovenous fistula (AV-shunt), which is known to produce heart failure due to volume overload. AV-shunt was indu